2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.
about
L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells.A peptide binding to the β-site of APP improves spatial memory and attenuates Aβ burden in Alzheimer's disease transgenic miceSmall molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloidThamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies.Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity.Plants traditionally used in age-related brain disorders (dementia): an ethanopharmacological survey.Interpreting Alzheimer's disease clinical trials in light of the effects on amyloid-β.Oligodendrocytes and Alzheimer's disease.Pharmacological Effects of Glycyrrhiza spp. and Its Bioactive Constituents: Update and Review.Protective and antioxidant effects of a chalconoid from Pulicaria incisa on brain astrocytes.Amyloid beta: structure, biology and structure-based therapeutic development.Cyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway.Natural Modulators of Amyloid-Beta Precursor Protein Processing.LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy.Screening of β-secretase and acetylcholinesterase inhibitors from plant resources.
P2860
Q34355809-F1C41561-6583-4548-B96E-4AF4058C09C9Q34469761-F8993BF2-534C-4E95-A39F-8C57C577218FQ36115392-4A171D04-1D39-4A82-993E-D247433876F8Q36802027-C3A82429-BBDA-4F23-AE72-E4EEF6311016Q37571958-A07E9FF1-1BED-4203-95A2-E000B4DF1E1EQ38026045-7C21E121-C50B-4D71-A633-379E63192F65Q38075593-8142FDFF-B8B0-4D34-9C05-7E14F5B14312Q38230384-902BA4D6-3270-4B4A-BE17-BC18FAFDD031Q38497880-9862FCE5-6E75-42DD-BBD9-9CEBD345CC44Q38606273-DD4DD44F-4F50-4C6F-BD8E-001E4E37217BQ38992158-4FD5790E-6F9F-4C1E-A450-655FFE4B4140Q39437881-9CECA055-1E6B-4F99-86C1-7734E0A8A6EBQ41679990-E3C72405-16BB-4485-87A2-D03ADBB5157DQ42142611-44DB074C-59A4-413C-94C6-AE5D610529B1Q47993126-56B0F6E0-7F05-4A91-9F58-62A9DB4418D4Q48606604-CEDBF5C7-36A6-4782-9812-60F853B37520
P2860
2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@en
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@nl
type
label
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@en
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@nl
prefLabel
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@en
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@nl
P2093
P2860
P1476
2,2',4'-trihydroxychalcone fro ...... tes memory impairment in mice.
@en
P2093
Chenjing Li
Hualiang Jiang
Zhengyi Yang
Zhiyuan Zhu
P2860
P304
P356
10.1111/J.1471-4159.2010.06751.X
P407
P50
P577
2010-04-19T00:00:00Z