Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression. - Wikidata - awgldk - TriplyDB

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

http://www.wikidata.org/entity/Q39720686

about

Fragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effect Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome.Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review.Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.Cloned human FMR1 trinucleotide repeats exhibit a length- and orientation-dependent instability suggestive of in vivo lagging strand secondary structure.Increase of FMRP expression, raised levels of FMR1 mRNA, and clonal selection in proliferating cells with unmethylated fragile X repeat expansions: a clue to the sex bias in the transmission of full mutations?Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma.Human pluripotent stem cells in modeling human disorders: the case of fragile X syndrome.Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine.DNA hypermethylation in gastric cancer.In vitro reactivation of the FMR1 gene involved in fragile X syndrome.

P2860

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P2860

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

http://www.wikidata.org/entity/Q39720686

description

1997 nî lūn-bûn

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1997年の論文

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1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

1997年论文

@zh

1997年论文

@zh-cn

name

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@en

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@nl

type

label

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@en

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@nl

prefLabel

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@en

Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

@nl

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Nucleic Acids Research

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Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.

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Sandberg G

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Schalling M

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P2860

The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

CpG-rich islands and the function of DNA methylation

Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Inheritance of the fragile X syndrome: size of the fragile X premutation is a major determinant of the transition to full mutation

Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

Fragile-X syndrome: unique genetics of the heritable unstable element

Instability of the CGG repeat and expression of the FMR1 protein in a male fragile X patient with a lung tumor.

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