Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation.
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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteinsDecoding the phosphorylation code in Hedgehog signal transductionPhosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse developmentCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedRegulation of protein stability by GSK3 mediated phosphorylation.Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase AInhibition of the nuclear import of cubitus interruptus by roadkill in the presence of strong hedgehog signal.Mechanism and evolution of cytosolic Hedgehog signal transductionThe Kto-Skd complex can regulate ptc expression by interacting with Cubitus interruptus (Ci) in the Hedgehog signaling pathway.CULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clockSu(fu) switches Rdx functions to fine-tune hedgehog signaling in the Drosophila wing disk.The role of kinases in the Hedgehog signalling pathway.Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activatorCSN-mediated deneddylation differentially modulates Ci(155) proteolysis to promote Hedgehog signalling responsesHedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responsesThe hedgehog/Gli signaling paradigm in prostate cancerHyperplastic discs differentially regulates the transcriptional outputs of hedgehog signalingContributions of Costal 2-Fused interactions to Hedgehog signaling in DrosophilaHedgehog signaling in prostate epithelial-mesenchymal growth regulation.Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.Regulation of stem cells by intersecting gradients of long-range niche signalsThe phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.Oskar is targeted for degradation by the sequential action of Par-1, GSK-3, and the SCF⁻Slimb ubiquitin ligase.A quantification of pathway components supports a novel model of Hedgehog signal transductionMultiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligaseThe hypoparathyroidism-associated mutation in Drosophila Gcm compromises protein stability and glial cell formation.Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling.The Hedgehog signal transduction network.Primary cilia and graded Sonic Hedgehog signaling.Transcriptional regulation of graded Hedgehog signalingDecoding Ci: from partial degradation to inhibition.The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.Distinct Biochemical Activities of Eyes absent During Drosophila Eye Development.CK1 in Developmental Signaling: Hedgehog and Wnt.Influenza NS1 directly modulates Hedgehog signaling during infection.Costal 2 interactions with Cubitus interruptus (Ci) underlying Hedgehog-regulated Ci processingThe emerging roles of phosphatases in Hedgehog pathway.A unique protection signal in Cubitus interruptus prevents its complete proteasomal degradationLigand-independent activation of the Hedgehog pathway displays non-cell autonomous proliferation during eye development in Drosophila.
P2860
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P2860
Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@en
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@nl
type
label
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@en
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@nl
prefLabel
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@en
Regulation of Ci-SCFSlimb bind ...... ctivity by Ci phosphorylation.
@nl
P2860
P1433
P1476
Regulation of Ci-SCFSlimb bind ...... activity by Ci phosphorylation
@en
P2093
Daniel Kalderon
Qianhe Zhou
P2860
P304
P356
10.1016/J.DEVCEL.2007.09.006
P407
P577
2007-10-01T00:00:00Z