Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.

Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.

Item
http://www.wikidata.org/entity/Q39732707
Towards a rational design of solid drug nanoparticles with optimised pharmacological properties.Physiology-based IVIVE predictions of tramadol from in vitro metabolism data.Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz.The role of quantitative ADME proteomics to support construction of physiologically based pharmacokinetic models for use in small molecule drug development.Application of physiologically based pharmacokinetic modeling to predict acetaminophen metabolism and pharmacokinetics in childrenA role for cytochrome b5 in the In vivo disposition of anticancer and cytochrome P450 probe drugs in mice.Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.Antiretroviral solid drug nanoparticles with enhanced oral bioavailability: production, characterization, and in vitro-in vivo correlation.Pharmacokinetic and pharmacodynamic analysis of efavirenz dose reduction using an in vitro-in vivo extrapolation model.Physiologically Based Pharmacokinetic Modelling of Cytochrome P450 2C9-Related Tolbutamide Drug Interactions with Sulfaphenazole and Tasisulam.Direct and quantitative evaluation of the human CYP3A4 contribution (fm) to drug clearance using the in vitro SILENSOMES model.Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims.Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine.
P2860

Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.

Item
http://www.wikidata.org/entity/Q39732707
description
2011 nî lūn-bûn
@nan
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Are there differences in the c ...... -system extrapolation factors.
@en
Are there differences in the c ...... -system extrapolation factors.
@nl
type
label
Are there differences in the c ...... -system extrapolation factors.
@en
Are there differences in the c ...... -system extrapolation factors.
@nl
prefLabel
Are there differences in the c ...... -system extrapolation factors.
@en
Are there differences in the c ...... -system extrapolation factors.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Are there differences in the c ...... -system extrapolation factors.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698