IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells.
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Regulatory gene network circuits underlying T cell development from multipotent progenitorsATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesProgressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infectionDynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR allelesCytokine Receptor Endocytosis: New Kinase Activity-Dependent and -Independent Roles of PI3K.Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cellsIncreased bone marrow interleukin-7 (IL-7)/IL-7R levels but reduced IL-7 responsiveness in HIV-positive patients lacking CD4+ gain on antiviral therapyAberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis.CD127 expression, exhaustion status and antigen specific proliferation predict sustained virologic response to IFN in HCV/HIV co-infected individuals.Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade.The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.Hantaan virus infection induces both Th1 and ThGranzyme B+ cell immune responses that associated with viral control and clinical outcome in humansChaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.Clathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2.Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synoviumThe major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes.Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia.Extracellular adenosine regulates naive T cell development and peripheral maintenance.Eliminative signaling by Janus kinases: role in the downregulation of associated receptors.HCV infection selectively impairs type I but not type III IFN signaling.Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia.IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex.Cytokine signaling modulates blood-brain barrier function.Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survivalIL-7 signaling and CD127 receptor regulation in the control of T cell homeostasisInterleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.Quantitative Analysis of Endocytic Recycling of Membrane Proteins by Monoclonal Antibody-Based Recycling Assays.Synergistic effects of interleukin-7 and pre-T cell receptor signaling in human T cell development.Ephrinb1 and Ephrinb2 are associated with interleukin-7 receptor α and retard its internalization from the cell surface.In vitro HIV Type 1 infection indirectly alters CD127 expression on CD8(+) T cells.The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression.Recycled IL-7 Can Be Delivered to Neighboring T Cells.Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2.Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity.Transcriptional regulation of the IL-7Rα gene by dexamethasone and IL-7 in primary human CD8 T cells.IL-7 induces clathrin-mediated endocytosis of CD127 and subsequent degradation by the proteasome in primary human CD8 T cells.Mathematical Model of Naive T Cell Division and Survival IL-7 ThresholdsModulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2.
P2860
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P2860
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@en
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@nl
type
label
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@en
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@nl
prefLabel
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@en
IL-7 induces rapid clathrin-me ...... tion of IL-7Ralpha in T cells.
@nl
P50
P1433
P1476
IL-7 induces rapid clathrin-me ...... ation of IL-7Ralpha in T cells
@en
P2093
Gerry J Graham
P304
P356
10.1182/BLOOD-2009-10-246876
P407
P577
2010-02-26T00:00:00Z