Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration.
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In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin BArtonin E Induces Apoptosis via Mitochondrial Dysregulation in SKOV-3 Ovarian Cancer CellsCharacterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppressionUsing X-ray in-line phase-contrast imaging for the investigation of nude mouse hepatic tumorsCucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation.Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells.Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.Terpenoids as potential chemopreventive and therapeutic agents in liver cancerDevelopment and validation of a UPLC-MS/MS method for the determination of cucurbitacin B in rat plasma and application to a pharmacokinetic study.Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest.The effects of methanolic, chloroform, and ethylacetate extracts of the Cucurbita pepo L. on the delay type hypersensitivity and antibody production.Effect of ethanolic extract of Ecballium elaterium against Staphylococcus aureus and Candida albicansThe triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancerPTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.In vitro anticancer activity of Spondias pinnata bark on human lung and breast carcinoma.Heartwood extract of Acacia catechu induces apoptosis in human breast carcinoma by altering bax/bcl-2 ratio.Terpenoids: natural products for cancer therapy.Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Novel menadione hybrids: Synthesis, anticancer activity, and cell-based studies.Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors.2-aryl benzimidazole conjugate induced apoptosis in human breast cancer MCF-7 cells through caspase independent pathway.2-Anilino-3-Aroylquinolines as Potent Tubulin Polymerization Inhibitors.Apoptosis inducing ability of silver decorated highly reduced graphene oxide nanocomposites in A549 lung cancer.Synthesis and Biological Evaluation of 1,2,3-triazole tethered Pyrazoline and Chalcone Derivatives.Green synthesis of bacterial mediated anti-proliferative gold nanoparticles: inducing mitotic arrest (G2/M phase) and apoptosis (intrinsic pathway).Approach for chemosensitization of cisplatin-resistant ovarian cancer by cucurbitacin B.Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.Structural optimization and biological screening of a steroidal scaffold possessing cucurbitacin-like functionalities as B-Raf inhibitors.Alteration of Bax/Bcl-2 ratio contributes to Terminalia belerica-induced apoptosis in human lung and breast carcinoma.Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment.Pseudolaric Acid B induces caspase-dependent and caspase-independent apoptosis in u87 glioblastoma cells.Jaceosidin Induces Apoptosis in U87 Glioblastoma Cells through G2/M Phase Arrest.Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages.The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis.HPTLC Analysis of Bioactivity Guided Anticancer Enriched Fraction of Hydroalcoholic Extract of Picrorhiza kurroa.In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa.Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells.Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation.Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells.
P2860
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P2860
Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@en
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@nl
type
label
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@en
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@nl
prefLabel
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@en
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@nl
P2093
P1433
P1476
Cucurbitacin B induces apoptos ...... ctive via oral administration.
@en
P2093
Cheong Yip Ho
Fan Yan Meng
Kee Hung Chu
Kin Tak Chan
Melvin Toh
Tsz Shan Lam
Wai Him Lee
P304
P356
10.1016/J.CANLET.2010.01.029
P407
P577
2010-02-11T00:00:00Z