FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. - Wikidata - awgldk - TriplyDB

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.

http://www.wikidata.org/entity/Q39741057

about

Role of ABCC1 in export of sphingosine-1-phosphate from mast cells The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors The organization and consequences of eicosanoid signaling NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications The membrane organization of leukotriene synthesis An essential role of the Jak-2/STAT-3/cytosolic phospholipase A(2) axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motility Targeting sphingosine 1 phosphate receptor type 1 receptors in acute kidney injury.Mathematical modeling reveals kinetics of lymphocyte recirculation in the whole organism.Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient.P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis.Schistosome ABC multidrug transporters: From pharmacology to physiology.Fingolimod (FTY720) stimulates Ca(2+)/calcineurin signaling in fission yeast.An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease.Effector mechanisms in transplant rejection.Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit Immune response to xenobiotics in the skin: from contact sensitivity to drug allergy.Sphingosine 1-phosphate receptor modulators: a new class of immunosuppressants.Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.Unraveling the complexities of sphingosine-1-phosphate function: the mast cell model.Hyaluronan: a constitutive regulator of chemoresistance and malignancy in cancer cells.Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance.The multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma.Ouabain-induced alterations in ABCB1 of mesenteric lymph nodes and thymocytes of rats and mice ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer.FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells.Implications of chemokine receptors and inflammatory lipids in cancer.FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1.Multidrug transporter activity in lymphocytes.FTY720, a sphingosine 1-phosphate receptor modulator, inhibits CD1d-restricted NKT cells by suppressing cytokine production but not migration.CD4+ CD25+ CD62+ T-regulatory cell subset has optimal suppressive and proliferative potential.STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility.The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity.Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes.Non-specific anti-proliferative effect of FTY720, a derivative of fungal metabolite from Iscaria sinclarii.CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model.

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P2860

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes.

http://www.wikidata.org/entity/Q39741057

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@en

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

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type

label

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@en

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@nl

prefLabel

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@en

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@nl

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Journal of Clinical Investigation

P1476

FTY720 stimulates multidrug tr ...... ell chemotaxis to lymph nodes.

@en

P2093

Adam Yopp

http://www.w3.org/2001/XMLSchema#string

Gwendalyn J Randolph

http://www.w3.org/2001/XMLSchema#string

Jonathan S Bromberg

http://www.w3.org/2001/XMLSchema#string

Michael D Gunn

http://www.w3.org/2001/XMLSchema#string

Shaun M Honig

http://www.w3.org/2001/XMLSchema#string

Shuang Fu

http://www.w3.org/2001/XMLSchema#string

Xia Mao

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P2860

Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

Sphingosine kinase: a mediator of vital cellular functions

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

Multidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factor

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

Lymphocyte homing and homeostasis

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627-637

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10.1172/JCI200316200

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5

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111

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12618517

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P932

151892

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