Genetic analysis of beta1 integrin "activation motifs" in mice. - Wikidata - awgldk - TriplyDB

Genetic analysis of beta1 integrin "activation motifs" in mice.

Genetic analysis of beta1 integrin "activation motifs" in mice.

http://www.wikidata.org/entity/Q39741501

about

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects Integrin cytoplasmic tail interactions The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity Kindlin-2 controls bidirectional signaling of integrins Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion.New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering.The final steps of integrin activation: the end game Zasp regulates integrin activation.Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.The tail of integrin activation.Analysis of conserved residues in the betapat-3 cytoplasmic tail reveals important functions of integrin in multiple tissues.Contributions of the integrin β1 tail to cell adhesive forces.Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation.The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entry.Role of integrins in the assembly and function of hensin in intercalated cells Regulation of integrin activity and signalling The ins and outs of leukocyte integrin signaling.Focal adhesion complex proteins in epidermis and squamous cell carcinoma.Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.Kindling the flame of integrin activation and function with kindlins Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation.Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion: cell matrix receptors are trafficked through the late endosomal pathway in a way that dictates how cells migrate.β1 integrin NPXY motifs regulate kidney collecting-duct development and maintenance by induced-fit interactions with cytosolic proteins.Talin - the master of integrin adhesions.The RGD motif in fibronectin is essential for development but dispensable for fibril assembly.

P2860

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P2860

Genetic analysis of beta1 integrin "activation motifs" in mice.

http://www.wikidata.org/entity/Q39741501

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

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2006年學術文章

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2006年學術文章

@zh-hant

name

Genetic analysis of beta1 integrin "activation motifs" in mice.

@en

Genetic analysis of beta1 integrin "activation motifs" in mice.

@nl

type

label

Genetic analysis of beta1 integrin "activation motifs" in mice.

@en

Genetic analysis of beta1 integrin "activation motifs" in mice.

@nl

prefLabel

Genetic analysis of beta1 integrin "activation motifs" in mice.

@en

Genetic analysis of beta1 integrin "activation motifs" in mice.

@nl

P1433

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P1433

Journal of Cell Biology

P1476

Genetic analysis of beta1 integrin "activation motifs" in mice.

@en

P2093

Aleksandra Czuchra

http://www.w3.org/2001/XMLSchema#string

Hannelore Meyer

http://www.w3.org/2001/XMLSchema#string

P2860

Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins

Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha

Structure and function of the platelet integrin alphaIIbbeta3

A specific interface between integrin transmembrane helices and affinity for ligand

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

beta 1 integrin function in vivo: adhesion, migration and more

Consequences of lack of beta 1 integrin gene expression in mice

Talin binding to integrin beta tails: a final common step in integrin activation

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

P304

889-899

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scholarly article

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10.1083/JCB.200604060

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P433

6

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174

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Reinhard Fässler

Cord Brakebusch

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2006-09-05T00:00:00Z

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6836459

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2064342

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