SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control. - Wikidata - awgldk - TriplyDB

SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control.

SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control.

http://www.wikidata.org/entity/Q39742308

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The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator RBM4 down-regulates PTB and antagonizes its activity in muscle cell-specific alternative splicing RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage The RNA Splicing Response to DNA Damage Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function Tissue-specific and SRSF1-dependent splicing of fibronectin, a matrix protein that controls host cell invasion Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response.An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA.Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.TDP-43 regulates its mRNA levels through a negative feedback loop.Arginine methylation controls the subcellular localization and functions of the oncoprotein splicing factor SF2/ASF Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma Single molecule analysis of c-myb alternative splicing reveals novel classifiers for precursor B-ALL.Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer.Shuttling SR proteins: more than splicing factors.Splicing factor SF2/ASF rescues IL-2 production in T cells from systemic lupus erythematosus patients by activating IL-2 transcription.Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling.RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis Regulation of splicing factors by alternative splicing and NMD is conserved between kingdoms yet evolutionarily flexible.A role for the serine/arginine-rich (SR) protein B52/SRSF6 in cell growth and myc expression in Drosophila Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage.Alternative RNA splicing and cancer Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1 Methylxanthines Increase Expression of the Splicing Factor SRSF2 by Regulating Multiple Post-transcriptional Mechanisms The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation.SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention.Comparative expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1 in gastric and colorectal cancer A splicing-independent function of SF2/ASF in microRNA processing.PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells.RBM4-MEF2C network constitutes a feed-forward circuit that facilitates the differentiation of brown adipocytes The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes.SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles.Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia Non-coding functions of alternative pre-mRNA splicing in development.Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA.The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells.A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.

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SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control.

http://www.wikidata.org/entity/Q39742308

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2010 nî lūn-bûn

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Nature Structural & Molecular Biology

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SF2/ASF autoregulation involve ...... nal and translational control.

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Rahul Sinha

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Rotem Karni

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Shuying Sun

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Zuo Zhang

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P2860

Ultraconserved Elements in the Human Genome

Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins

Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

AU-rich elements and associated factors: are there unifying principles?

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

A novel role for shuttling SR proteins in mRNA translation

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

The impact of microRNAs on protein output

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

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306-312

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10.1038/NSMB.1750

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3

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17

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Adrian Robert Krainer

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2010-02-07T00:00:00Z

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41414492

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20139984

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2921916

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