p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. - Wikidata - awgldk - TriplyDB

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

http://www.wikidata.org/entity/Q39742724

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SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation SCCRO promotes glioma formation and malignant progression in mice Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure.New and emerging factors in tumorigenesis: an overview Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer.Pathway-driven discovery of rare mutational impact on cancer Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.Oscillations of the p53-Akt network: implications on cell survival and death Gene medicine for cancer treatment: commercially available medicine and accumulated clinical data in China p53 regulates metanephric development AKT pathway genes define 5 prognostic subgroups in glioblastoma.WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis.The cooperative effect of p53 and Rb in local nanotherapy in a rabbit VX2 model of hepatocellular carcinoma.Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death.MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer RNAi knockdown of PIK3CA preferentially inhibits invasion of mutant PIK3CA cells Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice.Molecular genetics of human cervical cancer: role of papillomavirus and the apoptotic cascade.DNA Copy Number Aberrations, and Human Papillomavirus Status in Penile Carcinoma. Clinico-Pathological Correlations and Potential Driver Genes.The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck.Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities.Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis.LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins Tumour and dendrimers: a review on drug delivery aspects.The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.PIK3CA alterations in Middle Eastern ovarian cancers.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Expression of PH Domain Leucine-rich Repeat Protein Phosphatase, Forkhead Homeobox Type O 3a and RAD51, and their Relationships with Clinicopathologic Features and Prognosis in Ovarian Serous Adenocarcinoma.Molecular biology of squamous cell carcinoma of the head and neck: relevance and therapeutic implications.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross-talk, and therapies.Defining the genomic landscape of head and neck cancers through next-generation sequencing.Molecular Targeting of Growth Factor Receptor Signaling in Radiation Oncology.Helicobacter pylori Infection Activates the Akt-Mdm2-p53 Signaling Pathway in Gastric Epithelial Cells.

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P2860

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

http://www.wikidata.org/entity/Q39742724

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@en

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@nl

type

label

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@en

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@nl

prefLabel

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@en

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

@nl

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Genes & Development

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p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.

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P2093

Andy Goberdhan

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Archontoula Stoffel

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Arnold J Levine

http://www.w3.org/2001/XMLSchema#string

Bhuvanesh Singh

http://www.w3.org/2001/XMLSchema#string

Christine Walsh

http://www.w3.org/2001/XMLSchema#string

Ivan Ngai

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Pabbathi G Reddy

http://www.w3.org/2001/XMLSchema#string

Pornchai O-Charoenrat

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Pulivarthi H Rao

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Su Dao

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P2860

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

PIK3CA as an oncogene in cervical cancer

Regulation of PTEN transcription by p53

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Cellular survival: a play in three Akts

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

Cancer statistics, 2000.

Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.

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984-993

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10.1101/GAD.973602

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8

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16

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11407290

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11959846

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152354

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