Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. - Wikidata - awgldk - TriplyDB

Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.

Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.

http://www.wikidata.org/entity/Q39745939

about

MicroRNAs in the DNA Damage/Repair Network and Cancer Mechanisms of change in gene copy number The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression Modulation of mismatch repair and genomic stability by miR-155 MiR-210--micromanager of the hypoxia pathway Aneuploidy: cells losing their balance Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression New insights and challenges in mismatch repair: getting over the chromatin hurdle Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity MicroRNA regulation of DNA repair gene expression in hypoxic stress Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress Improving the radiosensitivity of radioresistant and hypoxic glioblastoma.Somatic CTG*CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy.Deciphering the molecular adaptation of the king scallop (Pecten maximus) to heat stress using transcriptomics and proteomics.Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli.Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression A microhomology-mediated break-induced replication model for the origin of human copy number variation.A possible link between iron deficiency and gastrointestinal carcinogenesis.Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones Hypoxic tumor microenvironment and cancer cell differentiation.Hypoxia and regulation of cancer cell stemness.Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms.Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1 Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells.Tumor hypoxia and genetic alterations in sporadic cancers.Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phenotypes through activation of epidermal growth factor receptor and hypoxia-inducible factor-2α.A study of molecular signals deregulating mismatch repair genes in prostate cancer compared to benign prostatic hyperplasia.Gene expression analysis of tumor spheroids reveals a role for suppressed DNA mismatch repair in multicellular resistance to alkylating agents.Thoughts on aneuploidy.Mutation as a stress response and the regulation of evolvability

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Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.

http://www.wikidata.org/entity/Q39745939

description

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2003年學術文章

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name

Decreased expression of the DN ...... xic stress in mammalian cells.

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Decreased expression of the DN ...... xic stress in mammalian cells.

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type

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Decreased expression of the DN ...... xic stress in mammalian cells.

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Decreased expression of the DN ...... xic stress in mammalian cells.

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prefLabel

Decreased expression of the DN ...... xic stress in mammalian cells.

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Decreased expression of the DN ...... xic stress in mammalian cells.

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Molecular and Cellular Biology

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Decreased expression of the DN ...... xic stress in mammalian cells.

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Denise Campisi

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Frank Giordano

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Jianling Yuan

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Latha Narayanan

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Peter M Glazer

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Randall S Johnson

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Ranjit S Bindra

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Ryan Jensen

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Sara Rockwell

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Valia T Mihaylova

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P2860

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

A conserved family of prolyl-4-hydroxylases that modify HIF

Hypoxia and oxidative stress. Tumour hypoxia--therapeutic considerations

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

Human rad21 gene, hHR21(SP), is downregulated by hypoxia in human tumor cells

Biochemistry and genetics of eukaryotic mismatch repair

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