Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate-binding sites in a single transporter.
about
Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesNonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substratesThe atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitorsStructure-function studies of the SLC17 transporter sialin identify crucial residues and substrate-induced conformational changesThe high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.Studies of the biogenic amine transporters. 14. Identification of low-efficacy "partial" substrates for the biogenic amine transportersClinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental studyMutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology modelMolecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters.Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells.Monoamine transporter structure, function, dynamics, and drug discovery: a computational perspective.Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding SitesSubstrate and drug binding sites in LeuT.Impact of disruption of secondary binding site S2 on dopamine transporter function.Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding4-Methylthioamphetamine increases dopamine in the rat striatum and has rewarding effects in vivo.
P2860
Q26745421-75DD78FB-5B3F-42DA-A4F7-874E15D2B150Q26853319-7DE7BFFA-F4A3-4C0B-B350-8C38347C8BCAQ28477546-3B2E0FAC-C042-46AC-B38D-F4E68AF9E30BQ33911345-ADD83B6A-CBBC-4D88-9F58-57F496163479Q34137102-22609D53-20F3-43FE-862E-1914D558771FQ34249270-5295CBD6-B639-445A-9893-4465C1CF1D37Q34408564-19FFCB5E-7EC8-435E-BE9D-5BA509F0F61BQ34597890-25CFD758-9FE2-4A02-81AF-7E7462FEF99CQ35123142-2C1242D7-A318-4DE3-9E87-5607BAC5399DQ35643579-3048B5E6-6450-4EC5-A90F-E2CA5483B557Q36331487-F7EE2D35-5A08-4B59-9A3F-198CAE21C91DQ36335545-6F031CAA-0A79-4367-B737-F1AF9114470BQ37064777-F6DE4D14-8A4E-44EB-AC05-EB09ACF664B6Q37782457-8C345EB2-C7FC-4DE5-9820-C96F2A1C6AE4Q38868543-A713C778-5453-4A28-B58C-AEE5D459740FQ40803358-456A1623-8C01-4E5A-A7D6-09E7BFADA0FBQ43964442-A9EEA84E-6D6E-4B5B-BDA9-4DE41D33FBD6
P2860
Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate-binding sites in a single transporter.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Bivalent phenethylamines as no ...... sites in a single transporter.
@en
Bivalent phenethylamines as no ...... sites in a single transporter.
@nl
type
label
Bivalent phenethylamines as no ...... sites in a single transporter.
@en
Bivalent phenethylamines as no ...... sites in a single transporter.
@nl
prefLabel
Bivalent phenethylamines as no ...... sites in a single transporter.
@en
Bivalent phenethylamines as no ...... sites in a single transporter.
@nl
P2093
P2860
P1476
Bivalent phenethylamines as no ...... sites in a single transporter
@en
P2093
Maarten E A Reith
Sreeman Mamidyala
Swati Biswas
P2860
P304
P356
10.1111/J.1471-4159.2010.06583.X
P407
P577
2010-01-12T00:00:00Z