Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.
about
Comparative genomics and molecular dynamics of DNA repeats in eukaryotesAdvances in mechanisms of genetic instability related to hereditary neurological diseases.The balancing act of DNA repeat expansionsMolecular mechanism of resolving trinucleotide repeat hairpin by helicasesRapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiaeMrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.Srs2: the "Odd-Job Man" in DNA repair.Histone deacetylase complexes promote trinucleotide repeat expansionsPotassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse modelUnwinding of synthetic replication and recombination substrates by Srs2.Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination.CAG*CTG repeat instability in cultured human astrocytesHighly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast.Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination.Repeat instability during DNA repair: Insights from model systemsInstability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesisHistone deacetylase complexes as caretakers of genome stability.The Werner syndrome protein promotes CAG/CTG repeat stability by resolving large (CAG)(n)/(CTG)(n) hairpinsDual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylationMutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells.ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.Base excision repair in physiology and pathology of the central nervous systemReplication fork stalling at natural impediments.Transcription destabilizes triplet repeatsFunctional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.The yin and yang of repair mechanisms in DNA structure-induced genetic instability.Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms.Replication stalling and DNA microsatellite instability.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Break-induced replication: an unhealthy choice for stress relief?Role of recombination and replication fork restart in repeat instability.Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients.The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats.Expansion of Interstitial Telomeric Sequences in Yeast.HFM1, the human homologue of yeast Mer3, encodes a putative DNA helicase expressed specifically in germ-line cells.
P2860
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P2860
Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
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name
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@en
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@nl
type
label
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@en
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@nl
prefLabel
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@en
Saccharomyces cerevisiae Srs2 ...... ions of trinucleotide repeats.
@nl
P2860
P1476
Saccharomyces cerevisiae Srs2 ...... sions of trinucleotide repeats
@en
P2093
Saumitri Bhattacharyya
P2860
P304
P356
10.1128/MCB.24.17.7324-7330.2004
P407
P50
P577
2004-09-01T00:00:00Z