Identification of residues contributing to the ATP binding site of Kir6.2.
about
Noble gas xenon is a novel adenosine triphosphate-sensitive potassium channel openerHow ATP inhibits the open K(ATP) channelNovel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces.Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactionsA gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome.Concerted gating mechanism underlying KATP channel inhibition by ATP.Muscle KATP channels: recent insights to energy sensing and myoprotectionElucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach.Regulation of the ATP-sensitive potassium channel subunit, Kir6.2, by a Ca2+-dependent protein kinase CATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neuronsATP-sensitive K+ channel channel/enzyme multimer: metabolic gating in the heart.Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors.Functional and Modeling Studies of the Transmembrane Region of the TRPM8 ChannelLigand-dependent linkage of the ATP site to inhibition gate closure in the KATP channelRegulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II.ATP-sensitive potassium channels: metabolic sensing and cardioprotection.Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.Decomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channelsStructural Basis for Differences in Dynamics Induced by Leu Versus Ile Residues in the CD Loop of Kir ChannelsCurrent understanding of K ATP channels in neonatal diseases: focus on insulin secretion disorders.Rebuilding a macromolecular membrane complex at the atomic scale: case of the Kir6.2 potassium channel coupled to the muscarinic acetylcholine receptor M2.ATP modulation of Ca2+ release by type-2 and type-3 inositol (1, 4, 5)-triphosphate receptors. Differing ATP sensitivities and molecular determinants of action.Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2.Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids.An inwardly rectifying potassium channel in apical membrane of Calu-3 cells.Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.Control of Kir channel gating by cytoplasmic domain interface interactionsLipids modulate ligand binding to sulphonylurea receptors.Regulation of action potential duration under acute heat stress by I(K,ATP) and I(K1) in fish cardiac myocytes.Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
P2860
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P2860
Identification of residues contributing to the ATP binding site of Kir6.2.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Identification of residues contributing to the ATP binding site of Kir6.2.
@en
Identification of residues contributing to the ATP binding site of Kir6.2.
@nl
type
label
Identification of residues contributing to the ATP binding site of Kir6.2.
@en
Identification of residues contributing to the ATP binding site of Kir6.2.
@nl
prefLabel
Identification of residues contributing to the ATP binding site of Kir6.2.
@en
Identification of residues contributing to the ATP binding site of Kir6.2.
@nl
P2093
P2860
P356
P1433
P1476
Identification of residues contributing to the ATP binding site of Kir6.2.
@en
P2093
Frances M Ashcroft
Mark S P Sansom
Phillippa Jones
Shozeb Haider
Stefan Trapp
P2860
P304
P356
10.1093/EMBOJ/CDG282
P407
P577
2003-06-01T00:00:00Z