pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.
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In vivo Magnetic Resonance Metabolic and Morphofunctional Fingerprints in Experimental Models of Human Ovarian CancerWays to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytesTM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cellsThe tumor microenvironment and strategies to improve drug distributionThe spatial organization of proton and lactate transport in a rat brain tumorExosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatinAcidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitorsCancer: fundamentals behind pH targeting and the double-edged approachA Quick Responsive Fluorogenic pH Probe for Ovarian Tumor Imaging.Effect of Modified Alkaline Supplementation on Syngenic Melanoma Growth in CB57/BL MiceEffects of omeprazole in improving concurrent chemoradiotherapy efficacy in rectal cancerEvaluations of extracellular pH within in vivo tumors using acidoCEST MRIIn vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionProton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cellsMicroenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.Human voltage-gated proton channel hv1: a new potential biomarker for diagnosis and prognosis of colorectal cancer.Modulation of autophagic activity by extracellular pH.Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagyLansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors.Clinicopathological and biological significance of human voltage-gated proton channel Hv1 protein overexpression in breast cancer.Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancerCotreatment with dichloroacetate and omeprazole exhibits a synergistic antiproliferative effect on malignant tumors.Autophagy is a protective mechanism for human melanoma cells under acidic stress.Exosome removal as a therapeutic adjuvant in cancer.Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors.Evidence-based support for the use of proton pump inhibitors in cancer therapyA comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH.Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment.Importance of the difference in surface pressures of the cell membrane in doxorubicin resistant cells that do not express Pgp and ABCG2.Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?Proton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance.The Function of V-ATPases in CancerProton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bedCariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies.Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase.Regulation and roles of bicarbonate transporters in cancer.Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy.Imaging pH and metastasis.
P2860
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P2860
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@en
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@nl
type
label
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@en
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@nl
prefLabel
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@en
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@nl
P2093
P2860
P50
P356
P1476
pH-dependent antitumor activit ...... y inhibition of tumor acidity.
@en
P2093
Antonello Villa
Elisabetta Iessi
Franca Podo
Francesco Lozupone
Manuela Iero
Maria Lucia Marino
Mariantonia Logozzi
Pamela Della Mina
P2860
P304
P356
10.1002/IJC.25009
P50
P577
2010-07-01T00:00:00Z