Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
about
Improved methods for the generation of human gene knockout and knockin cell linesAdeno-associated virus vector integrationZinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modificationsFacile methods for generating human somatic cell gene knockouts using recombinant adeno-associated virusesGene therapy for severe combined immunodeficiency: are we there yet?Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline.Genome-editing Technologies for Gene and Cell TherapyTowards a new era in medicine: therapeutic genome editingEngineered Viruses as Genome Editing DevicesProduction of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transferEfficient and versatile CRISPR engineering of human neurons in culture to model neurological disordersA look to future directions in gene therapy research for monogenic diseases.Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correctionDirected evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells.Nemo-like kinase is critical for p53 stabilization and function in response to DNA damageChromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast.A one-step cloning method for the construction of somatic cell gene targeting vectors: application to production of human knockout cell linesSimple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene.AAV hits the genomic bull's-eye.Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template.Zinc-finger nucleases for somatic gene therapy: the next frontier.Efficient gene targeting mediated by a lentiviral vector-associated meganucleaseA genome-wide map of adeno-associated virus-mediated human gene targetingVersatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.AAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivoIn vivo genome editing of the albumin locus as a platform for protein replacement therapyPrecise hit: adeno-associated virus in gene targeting.DNA damage promotes herpes simplex virus-1 protein expression in a neuroblastoma cell line.Development of human gene reporter cell lines using rAAV mediated homologous recombinationGenome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications.Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotypeRecombinant adeno-associated virus transduction and integration.Epitope tagging of endogenous genes in diverse human cell lines.Using homologous recombination to manipulate the genome of human somatic cells.AAV-mediated gene targeting methods for human cellsTargeted correction of single-base-pair mutations with adeno-associated virus vectors under nonselective conditions.Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs.Development of gene therapy for blood disorders: an update.
P2860
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P2860
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@en
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@nl
type
label
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@en
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@nl
prefLabel
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@en
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@nl
P2093
P2860
P1476
Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks.
@en
P2093
David Baltimore
Matthew D Weitzman
Matthew H Porteus
P2860
P304
P356
10.1128/MCB.23.10.3558-3565.2003
P407
P577
2003-05-01T00:00:00Z