XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. - Wikidata - awgldk - TriplyDB

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

http://www.wikidata.org/entity/Q39791125

about

CtIP is required to initiate replication-dependent interstrand crosslink repair Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2 Molecular pathogenesis and clinical management of Fanconi anemia How the fanconi anemia pathway guards the genome The Fanconi anemia pathway and DNA interstrand cross-link repair Pathways for repairing and tolerating the spectrum of oxidative DNA lesions DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease Fanconi anaemia and the repair of Watson and Crick DNA crosslinks Advances in understanding the complex mechanisms of DNA interstrand cross-link repair ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers DNA interstrand crosslink repair in mammalian cells: step by step.Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Initiation of DNA interstrand cross-link repair in mammalian cells.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody.DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer.Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition.Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks.XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck.Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process.Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase A new sub-pathway of long-patch base excision repair involving 5' gap formation.RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models.UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.

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P2860

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

http://www.wikidata.org/entity/Q39791125

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@en

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@nl

type

label

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@en

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@nl

prefLabel

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@en

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.

@nl

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P1433

Molecular and Cellular Biology

P1476

XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair

@en

P2093

Alan D'Andrea

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Anderson T Wang

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Anna L Olsen

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Laura J Niedernhofer

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Patricia Stuckert

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Roland Kanaar

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P2860

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation

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6427-6437

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scholarly article

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10.1128/MCB.00086-09

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24

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29

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Katsuhiro Hanada

Nikhil R Bhagwat

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2009-10-05T00:00:00Z

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19805513

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2786876

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