FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. - Wikidata - awgldk - TriplyDB

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

http://www.wikidata.org/entity/Q34128701

about

RAD18-BRCTx interaction is required for efficient repair of UV-induced DNA damage Spartan/C1orf124 is important to prevent UV-induced mutagenesis FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Molecular pathogenesis and clinical management of Fanconi anemia Mutations of the SLX4 gene in Fanconi anemia Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway Role of Deubiquitinating Enzymes in DNA Repair The Fanconi anemia pathway and DNA interstrand cross-link repair Mechanism and regulation of incisions during DNA interstrand cross-link repair Diseases associated with defective responses to DNA damage The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition The structure of the FANCM–MHF complex reveals physical features for functional assembly Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response Postreplicative mismatch repair.The DNA Damage Response: Making It Safe to Play with Knives Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4 Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability Fanconi anaemia and the repair of Watson and Crick DNA crosslinks Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.Expanded roles of the Fanconi anemia pathway in preserving genomic stability CtIP mediates replication fork recovery in a FANCD2-regulated manner.SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.FAN1 variants identified in multiple-case early-onset breast cancer families via exome sequencing: no evidence for association with risk for breast cancer.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair.

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FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

http://www.wikidata.org/entity/Q34128701

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@ast

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@en

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@nl

type

label

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@ast

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@en

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@nl

prefLabel

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@ast

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@en

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@nl

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SCIENCE.1192656

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P1476

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.

@en

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Gargi Ghosal

http://www.w3.org/2001/XMLSchema#string

Jingsong Yuan

http://www.w3.org/2001/XMLSchema#string

Jun Huang

http://www.w3.org/2001/XMLSchema#string

Junjie Chen

http://www.w3.org/2001/XMLSchema#string

Ting Liu

http://www.w3.org/2001/XMLSchema#string

P2860

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

How the fanconi anemia pathway guards the genome

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Identification of novel restriction endonuclease-like fold families among hypothetical proteins.

The Fanconi anaemia/BRCA pathway

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

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693-696

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scholarly article

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10.1126/SCIENCE.1192656

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5992

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329

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2010-07-29T00:00:00Z

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45423888

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20671156

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