Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors.
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Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agentComputational insights for the discovery of non-ATP competitive inhibitors of MAP kinases4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms.Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics.Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer.Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signalingA high throughput assay to identify substrate-selective inhibitors of the ERK protein kinases.
P2860
Q28486289-A4419AA5-53B6-42DF-A7B0-54DE872CEA4CQ33593739-32F05AEA-AC82-4119-8190-4926D1529BC0Q33619953-18CBA5B7-C4A2-42DF-B881-0E58051D1634Q33756524-863594D1-64B8-4778-B462-1DEEDC7ECFDDQ35740070-975AD5D4-54DC-44C8-A5F4-DD4703011A46Q36872318-819B22CD-06AF-40B6-B2CE-898793941177Q50925733-55C6B742-7E50-462F-BE14-D1A693298723
P2860
Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@en
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@nl
type
label
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@en
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@nl
prefLabel
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@en
Structure-activity relationshi ...... te-specific ERK1/2 inhibitors.
@nl
P2093
P50
P1476
Structure-activity relationshi ...... ate-specific ERK1/2 inhibitors
@en
P2093
Adnan Al-Ayoubi
Scott T Eblen
Shijun Zhang
Steven Grant
Tailiang Guo
Tri Nguyen
P304
P356
10.1016/J.BMCL.2009.09.057
P407
P577
2009-09-18T00:00:00Z