about
Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cellsCytokines and chemokines: At the crossroads of cell signalling and inflammatory diseaseClass II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cellsCalpain-10: from genome search to function.Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion.Emerging functions of the calpain superfamily of cysteine proteases in neuroendocrine secretory pathways.Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell.Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.Snapin mediates insulin secretory granule docking, but not trans-SNARE complex formation.High extracellular glucose inhibits exocytosis through disruption of syntaxin 1A-containing lipid rafts.Involvement of calpain and synaptotagmin Ca2+ sensors in hormone secretion from excitable endocrine cells.Differential cytokine secretion results from p65 and c-Rel NF-κB subunit signaling in peripheral blood mononuclear cells of TNF receptor-associated periodic syndrome patients.Lessons from anti-TNF biologics: infliximab failure in a TRAPS family with the T50M mutation in TNFRSF1A.Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome.Abnormal tumor necrosis factor receptor I cell surface expression and NF-kappaB activation in tumor necrosis factor receptor-associated periodic syndrome.A novel TNFRSF1A splice mutation associated with increased nuclear factor kappaB (NF-kappaB) transcription factor activation in patients with tumour necrosis factor receptor associated periodic syndrome (TRAPS).Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-kappaB activation.Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake.Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK.Fatty acyl CoA-mediated inhibition of endoplasmic reticulum assembly.Coordinated control of both insulin secretion and insulin action through calpain-10-mediated regulation of exocytosis?A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum.Protein traffic from the secretory pathway to the endosomal system in pancreatic beta-cells.The identification of TNFR5 as a therapeutic target in diabetes.Type 2 diabetes – An autoinflammatory disease driven by metabolic stressEffect of glucolipotoxicity and rosiglitazone upon insulin secretionIdentification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretionThe Physiological Roles of Carnosine and β-Alanine in Exercising Human Skeletal Muscle
P50
Q24306602-171754F3-00DB-4547-83B2-054BDC588B31Q27015076-EB4BC24E-7C77-4A22-9C8B-79BA02FE32B8Q28575171-CE0B0A6A-093A-42F0-BEFA-AF63E34C9DB7Q34435033-3516E1FC-333F-459A-93A8-CE4D1B653BC9Q35485350-14B25181-DCA5-4679-8267-77E36178B18BQ36897442-BE30CB3F-2D32-4974-9473-36E87F3DFF26Q36899808-686D74B7-8A0D-4DA2-92B8-4E4665B5D171Q37412470-5E4866E3-6492-4834-857B-952A393802BAQ38788620-2DABE374-E8F9-4BA0-893B-8F216F1056F0Q39806498-B9AA81A2-9A25-409D-A544-EAEDB100E4A0Q40227321-B721D4DB-43E3-4F0E-84FC-9A59E6DD1061Q40330380-BB60BBDB-E6C7-4F02-BD29-EEFD02E80D67Q40340793-51EB53A1-5A8A-4843-A3A8-DADC2D6058CAQ40398400-3BAF98B6-9189-4FD9-8675-5C1A79885134Q40430536-9D2B22C0-B8C5-440B-835B-4F40570A63E9Q40431832-646452B2-9545-4C2B-8F2C-FC33677A8176Q40499389-B5F5CA0D-CC8C-4E77-ADCF-84CCE449B9ADQ42683698-C23E03F0-E086-4914-ACA6-AC68FACE65B8Q44483164-E62BF257-C403-4E85-912B-A6C460A37519Q44994598-A3321C5C-8CA2-44BA-999A-C98261732DD5Q45868733-8F46701A-E882-4282-B510-36E011E5EEA3Q46009473-5D582BD1-00AB-436B-AA1F-1419CCF1781BQ52168541-2D09C8C1-5B69-4B2A-841E-2306DA72A681Q53809834-E7C27D22-5914-4965-BA42-B25D6694D29AQ59449554-C2DC4E6B-CE71-4E6D-8117-39098B270DE4Q61889320-6A4540A5-5E96-4FAA-97A6-B49F52FDF98EQ91070866-49B4FAEC-BA1E-41FB-BA79-A584495EEDB5Q91978951-2FEBA193-7145-4BA6-806E-6ED9F0576086
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Mark D Turner
@nl
Mark D Turner
@sl
Mark D. Turner
@en
Mark D. Turner
@es
type
label
Mark D Turner
@nl
Mark D Turner
@sl
Mark D. Turner
@en
Mark D. Turner
@es
prefLabel
Mark D Turner
@nl
Mark D Turner
@sl
Mark D. Turner
@en
Mark D. Turner
@es
P106
P1153
7403215326
P21
P31
P496
0000-0001-7175-1053