Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-kappaB activation.
about
Involvement of the same TNFR1 residue in mendelian and multifactorial inflammatory disorders.Falling into TRAPS--receptor misfolding in the TNF receptor 1-associated periodic fever syndromeTWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domainA pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS)Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion.The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathwayAbnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)Setting up TRAPS.Skin manifestations in tumor necrosis factor receptor-associated periodic syndrome (TRAPS).Tumor necrosis factor receptor-associated periodic syndrome as a model linking autophagy and inflammation in protein aggregation diseases.Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond.Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines.Latency can be conferred to a variety of cytokines by fusion with latency-associated peptide from TGF-β.A novel hybrid promoter responsive to pathophysiological and pharmacological regulationDifferential impact of high and low penetrance TNFRSF1A gene mutations on conventional and regulatory CD4+ T cell functions in TNFR1-associated periodic syndrome.Low TNF-induced NF-kappaB and p38 phosphorylation levels in leucocytes in tumour necrosis factor receptor-associated periodic syndrome.Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritisThe Tetracycline Responsive System.Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide.The classification, genetic diagnosis and modelling of monogenic autoinflammatory disorders
P2860
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P2860
Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-kappaB activation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en-gb
type
label
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en-gb
prefLabel
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en
Tumor necrosis factor receptor ...... ependent NF-kappaB activation.
@en-gb
P2093
P50
P356
P1476
Tumor necrosis factor receptor ...... dependent NF-kappaB activation
@en
P2093
Ebun Aganna
Graham A Hitman
Linda Hammond
Nasim Yousaf
Rita M Mirakian
Yuti Chernajovsky
P2860
P304
P356
10.1002/ART.21268
P577
2005-09-01T00:00:00Z