Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells.
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Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cellsPotential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactonePaclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress.Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ.Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation.Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3β and mTOR signaling pathways[Application of the Ca2+ indicator fluo-3 and fluo-4 in the process of H2O2 induced apoptosis of A549 cell].Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide.Chamaejasmin B exerts anti-MDR effect in vitro and in vivo via initiating mitochondria-dependant intrinsic apoptosis pathway.miR-3928 activates ATR pathway by targeting Dicer.Subamolide a induces mitotic catastrophe accompanied by apoptosis in human lung cancer cellsIdentifying reproducible cancer-associated highly expressed genes with important functional significances using multiple datasets.Endoplasmic-reticulum calcium depletion and disease.Selected terpenoids from medicinal plants modulate endoplasmic reticulum stress in metabolic disorders.Anticancer effect of Saussurea lappa extract via dual control of apoptosis and autophagy in prostate cancer cells.Costunolide induces lung adenocarcinoma cell line A549 cells apoptosis through ROS (reactive oxygen species)-mediated endoplasmic reticulum stress.Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells.Human leptin protein induces proliferation of A549 cells via inhibition of PKR-like ER kinase and activating transcription factor-6 mediated apoptosis.Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress.Ferruginol inhibits non-small cell lung cancer growth by inducing caspase-associated apoptosis.Saussurea lappa (Kuth root): review of its traditional uses, phytochemistry and pharmacologyAnti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review
P2860
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P2860
Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@en
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@nl
type
label
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@en
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@nl
prefLabel
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@en
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@nl
P2093
P921
P1433
P1476
Oxidative and endoplasmic reti ...... -small cell lung cancer cells.
@en
P2093
Chih-Jen Yang
Jen-Yu Hung
Ming-Shyan Huang
Po-Lin Kuo
Wen-Chiu Ni
Ya-Ling Hsu
Ying-Ming Tsai
P304
P356
10.1016/J.LUNGCAN.2009.07.017
P577
2009-08-22T00:00:00Z