Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells. - Wikidata - awgldk - TriplyDB

Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells.

Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells.

http://www.wikidata.org/entity/Q39052460

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Endocannabinoid system as a regulator of tumor cell malignancy - biological pathways and clinical significance Choline Metabolism Alteration: A Focus on Ovarian Cancer Choline metabolism-based molecular diagnosis of cancer: an update Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy.Magnetic resonance spectroscopy for detection of choline kinase inhibition in the treatment of brain tumors Choline kinase alpha-Putting the ChoK-hold on tumor metabolism.Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors.Choline transporter-like proteins CTLs/SLC44 family as a novel molecular target for cancer therapy.Stress management by autophagy: Implications for chemoresistance.RU486 Induces Pro-Apoptotic Endoplasmic Reticulum Stress Through the Induction of CHOP Expression by Enhancing C/EBPδ Expression in Human Renal Carcinoma Caki Cells.Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.Targeting Phospholipid Metabolism in Cancer.The roles of oxidative stress, endoplasmic reticulum stress, and autophagy in aldosterone/mineralocorticoid receptor-induced podocyte injury.Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress

P2860

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P2860

Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells.

http://www.wikidata.org/entity/Q39052460

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

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Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

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type

label

Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

@en

Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

@nl

prefLabel

Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

@en

Choline kinase inhibition indu ...... osis via CHOP in cancer cells.

@nl

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Cell Death and Disease

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Choline kinase inhibition indu ...... tosis via CHOP in cancer cells

@en

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A Cebrian

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J C Lacal Sanjuan

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M P Moyer

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T Gomez del Pulgar

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T Zimmerman

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P2860

Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

Roles of CHOP/GADD153 in endoplasmic reticulum stress

Kinetic and mechanistic characterisation of Choline Kinase-α

The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor

Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K

Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers

Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells

Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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e933

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10.1038/CDDIS.2013.453

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4

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Elsa Sanchez-Lopez

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2013-11-28T00:00:00Z

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259002403

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24287694

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endoplasmic reticulum

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3847329

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