9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
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NMR Fragment Screening Hit Induces Plasticity of BRD7/9 BromodomainsStructure-Based Design of an in Vivo Active Selective BRD9 InhibitorIdentification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach.Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.Progress in the Development of non-BET Bromodomain Chemical Probes.BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.Biological function and histone recognition of family IV bromodomain-containing proteins.1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Structural features and inhibitors of bromodomains.Bromodomain inhibitors and cancer therapy: From structures to applications.Unveiling the folding mechanism of the Bromodomains.Chemical probes and inhibitors of bromodomains outside the BET family.Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors.Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains
P2860
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P2860
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
@en
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
@nl
type
label
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
@en
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
@nl
prefLabel
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
@en
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
@nl
P2093
P2860
P50
P356
P1476
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
@en
P2093
Danette L Daniels
Gianluigi Lauro
Ines Bruno
Jacqui Mendez
Maria Strocchia
Sarah Picaud
Stefania Terracciano
P2860
P304
P356
10.1021/JM501893K
P407
P577
2015-03-05T00:00:00Z