Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition - Wikidata - awgldk - TriplyDB

Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition

Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition

http://www.wikidata.org/entity/Q39809931

about

Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells Micro-NMR for rapid molecular analysis of human tumor samples Cu-free click cycloaddition reactions in chemical biology Click chemistry in complex mixtures: bioorthogonal bioconjugation Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers.Pretargeted imaging and radioimmunotherapy of cancer using antibodies and bioorthogonal chemistry Bioorthogonal small molecule imaging agents allow single-cell imaging of MET Tetrazine-Containing Amino Acid for Peptide Modification and Live Cell Labeling (E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation.Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy.Site-specific labeling of proteins and peptides with trans-cyclooctene containing handles capable of tetrazine ligation.Bioorthogonal chemistry: recent progress and future directions.Magnetic nanoparticles for biomedical NMR-based diagnostics Magnetic Nanoparticles and microNMR for Diagnostic Applications.PEGylated click polypeptides synthesized by copper-free microwave-assisted thermal click polymerization for selective endotoxin removal from protein solutions.Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes.A metabolic alkene reporter for spatiotemporally controlled imaging of newly synthesized proteins in Mammalian cells.Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging.Fast hydrazone reactants: electronic and acid/base effects strongly influence rate at biological pH.Chemically modified antibodies as diagnostic imaging agents Radioiodinated O(6)-Benzylguanine derivatives containing an azido function.Fluorine-18 radiochemistry, labeling strategies and synthetic routes Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains.μHall chip for sensitive detection of bacteria Inverse electron demand Diels-Alder reactions of 1,2,3-triazines: pronounced substituent effects on reactivity and cycloaddition scope Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging.Biomedical applications of tetrazine cycloadditions.Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry.Click chemistry patents and their impact on drug discovery and chemical biology.Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation.An efficient and mild oxidant for the synthesis of s-tetrazines.(3,6-Dimethyl-1,2,4,5-tetra-zine-1,4-di-yl)bis-[(morpholin-4-yl)methanone].3,6-Bis(4-chloro-phen-yl)-N,N-bis-(1-phenyl-eth-yl)-1,2,4,5-tetra-zine-1,4-di-carboxamide.Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation.Enzyme-Controlled Intracellular Self-Assembly of (18)F Nanoparticles for Enhanced MicroPET Imaging of Tumor.Reactive polymer enables efficient in vivo bioorthogonal chemistry.

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P2860

Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition

http://www.wikidata.org/entity/Q39809931

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

@zh-my

2009年学术文章

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2009年學術文章

@yue

2009年學術文章

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2009年學術文章

@zh-hant

name

Fast and sensitive pretargeted ...... rans-cyclooctene cycloaddition

@en

Fast and sensitive pretargeted ...... ans-cyclooctene cycloaddition.

@nl

type

label

Fast and sensitive pretargeted ...... rans-cyclooctene cycloaddition

@en

Fast and sensitive pretargeted ...... ans-cyclooctene cycloaddition.

@nl

prefLabel

Fast and sensitive pretargeted ...... rans-cyclooctene cycloaddition

@en

Fast and sensitive pretargeted ...... ans-cyclooctene cycloaddition.

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P1433

Angewandte Chemie International Edition

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Fast and sensitive pretargeted ...... rans-cyclooctene cycloaddition

@en

P2093

Jered B Haun

http://www.w3.org/2001/XMLSchema#string

Neal K Devaraj

http://www.w3.org/2001/XMLSchema#string

Rabi Upadhyay

http://www.w3.org/2001/XMLSchema#string

Scott A Hilderbrand

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P2860

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

Tetrazine-based cycloadditions: application to pretargeted live cell imaging

Copper-free click chemistry for dynamic in vivo imaging

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

Chemistry in living systems

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

Epidermal growth factor receptor mutations in lung cancer

Arming antibodies: prospects and challenges for immunoconjugates.

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7013-7016

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10.1002/ANIE.200903233

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38

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48

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Ralph Weissleder

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26757803

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2790075

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