LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression. - Wikidata - awgldk - TriplyDB

LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.

LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.

http://www.wikidata.org/entity/Q39817827

about

The LMO2 oncogene regulates DNA replication in hematopoietic cells Inferring gene-phenotype associations via global protein complex network propagation Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells.The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells.LIM-domain-only proteins in cancer.LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF.Genetic susceptibility to neuroblastoma.Antiproliferative effects of a new α-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro.Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci.Anxious moments for the protein tyrosine phosphatase PTP1B.β-cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion?LMO4 modulates proliferation and differentiation of 3T3-L1 preadipocytes.Novel amplifications in pediatric medulloblastoma identified by genome-wide copy number profiling.iCopyDAV: Integrated platform for copy number variations-Detection, annotation and visualization.LMO4 mediates trastuzumab resistance in HER2 positive breast cancer cells.

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LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.

http://www.wikidata.org/entity/Q39817827

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

@zh-hant

name

LMO4 is an essential mediator ...... cancer cell cycle progression.

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LMO4 is an essential mediator ...... cancer cell cycle progression.

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type

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LMO4 is an essential mediator ...... cancer cell cycle progression.

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LMO4 is an essential mediator ...... cancer cell cycle progression.

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prefLabel

LMO4 is an essential mediator ...... cancer cell cycle progression.

@en

LMO4 is an essential mediator ...... cancer cell cycle progression.

@nl

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LMO4 is an essential mediator ...... cancer cell cycle progression.

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B Andersen

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D D Seachrist

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J Visvader

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M D Landis

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R A Keri

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P2860

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer.

ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas

Cardiac dysfunction in the trastuzumab clinical trials experience

ONCOMINE: a cancer microarray database and integrated data-mining platform

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

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