The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias - Wikidata - awgldk - TriplyDB

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

http://www.wikidata.org/entity/Q39830585

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A novel role of RASSF9 in maintaining epidermal homeostasis FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells Spanning the genomics era: the vital role of a single institution biorepository for childhood cancer research over a decade RASSF6; the Putative Tumor Suppressor of the RASSF Family Epigenomics of leukemia: from mechanisms to therapeutic applications RASSF tumor suppressor gene family: biological functions and regulation RASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma.An overview of genetics of paediatric rheumatic diseases.Silencing of RASSF3 by DNA hypermethylation is associated with tumorigenesis in somatotroph adenomas.Methylation of ras association domain protein 10 (RASSF10) promoter negative association with the survival of gastric cancer.N-terminal RASSF family: RASSF7-RASSF10.Ontology based molecular signatures for immune cell types via gene expression analysis Promoter methylation status of Ras-association domain family members in pheochromocytoma.RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.Pancreatic cancer patient survival correlates with DNA methylation of pancreas development genes.Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival.RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker Combined RASSF1A and RASSF2A Promoter Methylation Analysis as Diagnostic Biomarker for Bladder Cancer.RASSF6 exhibits promoter hypermethylation in metastatic melanoma and inhibits invasion in melanoma cells.Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma.RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma.RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.Aberrant Promoter Methylation of the Tumour Suppressor RASSF10 and Its Growth Inhibitory Function in Breast Cancer.RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma The epigenome as a potential mediator of cancer and disease prevention in prenatal development.Ras-association domain family 10 acts as a novel tumor suppressor through modulating MMP2 in hepatocarcinoma.Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma.The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation.Mammalian Hippo pathway: from development to cancer and beyond.DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia.Epigenetic regulation of cell signaling pathways in acute lymphoblastic leukemia.Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway.Ras signaling through RASSF proteins.The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein.RASSF2 methylation is a strong prognostic marker in younger age patients with Ewing sarcoma Epigenetic down regulation of RASSF10 and its possible clinical implication in prostate carcinoma.Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

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The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

http://www.wikidata.org/entity/Q39830585

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2009 nî lūn-bûn

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

The novel RASSF6 and RASSF10 c ...... ivated in childhood leukaemias

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The novel RASSF6 and RASSF10 c ...... vated in childhood leukaemias.

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type

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The novel RASSF6 and RASSF10 c ...... ivated in childhood leukaemias

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The novel RASSF6 and RASSF10 c ...... vated in childhood leukaemias.

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The novel RASSF6 and RASSF10 c ...... ivated in childhood leukaemias

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Molecular Cancer

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The novel RASSF6 and RASSF10 c ...... ivated in childhood leukaemias

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Daniel Catchpoole

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Farida Latif

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Luke B Hesson

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Mike Griffiths

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Wendy N Cooper

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P2860

The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Targeting RAS signalling pathways in cancer therapy

Identification of a novel Ras-regulated proapoptotic pathway

RASSF6 is a novel member of the RASSF family of tumor suppressors

Interpreting cDNA sequences: some insights from studies on translation

The Ras-association domain family (RASSF) members and their role in human tumourigenesis.

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10.1186/1476-4598-8-42

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8

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Thomas L Dunwell

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26333880

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