Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.
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Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilizationThe role of BH3-mimetic drugs in the treatment of pediatric hepatoblastomaSynergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanomaHA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol.A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2.Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapyEndoplasmic-reticulum calcium depletion and disease.Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.A novel SERCA inhibitor demonstrates synergy with classic SERCA inhibitors and targets multidrug-resistant AML.The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells.BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides.Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells.Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.Exploring the Structure-Activity Relationship and Mechanism of a Chromene Scaffold (CXL Series) for Its Selective Antiproliferative Activity toward Multidrug-Resistant Cancer Cells
P2860
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P2860
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@en
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@nl
type
label
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@en
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@nl
prefLabel
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@en
Dual mechanisms of sHA 14-1 in ...... ic reticulum and mitochondria.
@nl
P2093
P2860
P50
P356
P1476
Dual mechanisms of sHA 14-1 in ...... mic reticulum and mitochondria
@en
P2093
Anna A Bajer
Balasubramanian Srinivasan
Chengguo Xing
David Hermanson
Fawaz Al-Mousa
Francesco Michelangeli
Sadiya N Addo
Sonia Goutam Kumar Das
P2860
P304
P356
10.1124/MOL.109.055830
P577
2009-06-26T00:00:00Z