Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors. - Wikidata - awgldk - TriplyDB

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors.

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors.

http://www.wikidata.org/entity/Q39832611

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P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia Molecular and functional properties of P2X receptors--recent progress and persisting challenges Connexin hemichannel and pannexin channel electrophysiology: how do they differ?The pannexins: past and present Brilliant Blue Dyes in Daily Food: How Could Purinergic System Be Affected?The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.Sex-dependent gene regulatory networks of the heart rhythm.Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4.Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels Ivermectin-dependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X(7)-KO mice.Activation and regulation of purinergic P2X receptor channels Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors.The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice.ATP-P2X7 receptor signaling controls basal and TNFα-stimulated glial cell proliferation.Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury.Paroxetine suppresses recombinant human P2X7 responses ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.Cardioprotective Effects of Genistin in Rat Myocardial Ischemia-Reperfusion Injury Studies by Regulation of P2X7/NF-κB Pathway.FGF-1 Triggers Pannexin-1 Hemichannel Opening in Spinal Astrocytes of Rodents and Promotes Inflammatory Responses in Acute Spinal Cord Slices.P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway.PKC-dependent ERK phosphorylation is essential for P2X7 receptor-mediated neuronal differentiation of neural progenitor cells P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation.Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue Danger signalling during cancer cell death: origins, plasticity and regulation.Diadenosine tetraphosphate (Ap4A) inhibits ATP-induced excitotoxicity: a neuroprotective strategy for traumatic spinal cord injury treatment.Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel 18F-labelled PET tracer targeting P2X7.C terminus of the P2X7 receptor: treasure hunting.P2X receptor antagonists for pain management: examination of binding and physicochemical properties.P2X receptors as drug targets.P2X and P2Y nucleotide receptors as targets in cardiovascular disease.Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain.Heteromeric assembly of P2X subunits.The first CNS-active carborane: A novel P2X7 receptor antagonist with antidepressant activity.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Central sensitization of nociceptive neurons in rat medullary dorsal horn involves purinergic P2X7 receptors.Pharmacological properties of the rhesus macaque monkey P2X7 receptor.

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Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors.

http://www.wikidata.org/entity/Q39832611

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2009 nî lūn-bûn

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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type

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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British Journal of Pharmacology

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Mammalian P2X7 receptor pharma ...... rat and human P2X7 receptors.

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Diana L Donnelly-Roberts

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Marian T Namovic

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Michael F Jarvis

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Ping Han

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P2860

Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

Proteomic and functional evidence for a P2X7 receptor signalling complex

P2X7 receptor-Pannexin1 complex: pharmacology and signaling

Molecular physiology of P2X receptors

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat

Signaling at purinergic P2X receptors

Antagonism by the suramin analogue NF279 on human P2X(1) and P2X(7) receptors

The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

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