IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
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Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling ReviewedThe role of the Janus kinase family/signal transducer and activator of transcription signaling pathway in fibrotic renal diseasePotential role of the inflammasome-derived inflammatory cytokines in pulmonary fibrosisInvolvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cellsIL-18 induces profibrotic renal tubular cell injury via STAT3 activation.Signalling pathways involved in hypoxia-induced renal fibrosis.The effect of chronic candesartan therapy on the metabolic profile and renal tissue cytokine levels in the obese Zucker rat.Urinary kidney biomarkers for early detection of nephrotoxicity in clinical drug development.IL-27 Regulates IL-18 binding protein in skin resident cellsRenal IL-18 production is macrophage independent during obstructive injury.The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.Effects of interleukin-18 on cardiac fibroblast function and gene expressionIL-18 mediates proapoptotic signaling in renal tubular cells through a Fas ligand-dependent mechanismProfibrotic effect of interleukin-18 in HK-2 cells is dependent on stimulation of the Toll-like receptor 4 (TLR4) promoter and increased TLR4 expression.Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis.Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease.Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis.Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis.IL-18 activation is dependent on Toll-like receptor 4 during renal obstruction.The NLRP3 inflammasome in kidney disease and autoimmunity.AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β.Baicalein attenuates renal fibrosis by inhibiting inflammation via down-regulating NF-κB and MAPK signal pathways.Interleukin-18 stimulates a positive feedback loop during renal obstruction via interleukin-18 receptor.Is the inflammasome a potential therapeutic target in renal disease?Innate immunity and resistance to tolerogenesis in allotransplantationCellular senescence, senescence-associated secretory phenotype, and chronic kidney diseaseMitochondria Protection after Acute Ischemia Prevents Prolonged Upregulation of IL-1β and IL-18 and Arrests CKD.Lipopolysaccharide-Induced Acute Kidney Injury Is Dependent on an IL-18 Receptor Signaling Pathway.Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.Effects of cell-type-specific expression of a pan-caspase inhibitor on renal fibrogenesis.Pyroptosis in pterygium pathogenesis.The pathological role of IL-18Rα in renal ischemia/reperfusion injury.
P2860
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P2860
IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@en
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@nl
type
label
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@en
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@nl
prefLabel
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@en
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@nl
P2093
P356
P1433
P1476
IL-18 neutralization ameliorat ...... transition and renal fibrosis.
@en
P2093
Ahmad H Bani-Hani
Daniel R Meldrum
Hiroshi Asanuma
Honji Zhang
Jeffery A Leslie
Karen Hile
Kirstan K Meldrum
Matthew T Campbell
P2888
P304
P356
10.1038/KI.2009.216
P407
P577
2009-06-17T00:00:00Z
P5875
P6179
1011939377