Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics.
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Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutationsThe structural modifications induced by the M339F substitution in PBP2x from Streptococcus pneumoniae further decreases the susceptibility to beta-lactams of resistant strainsA PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibioticsA low-affinity penicillin-binding protein 2x variant is required for heteroresistance in Streptococcus pneumoniae.The ponA gene of Enterococcus faecalis JH2-2 codes for a low-affinity class A penicillin-binding protein.FemABX peptidyl transferases: a link between branched-chain cell wall peptide formation and beta-lactam resistance in gram-positive cocci.Reconstitution of membrane protein complexes involved in pneumococcal septal cell wall assemblyIdentification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria.Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin.BOCILLIN FL, a sensitive and commercially available reagent for detection of penicillin-binding proteins.Diversity of substitutions within or adjacent to conserved amino acid motifs of penicillin-binding protein 2X in cephalosporin-resistant Streptococcus pneumoniae isolates.Identification and characterization of the penicillin-binding protein 2a of Streptococcus pneumoniae and its possible role in resistance to beta-lactam antibiotics.All detectable high-molecular-mass penicillin-binding proteins are modified in a high-level beta-lactam-resistant clinical isolate of Streptococcus mitis.Glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae is membrane associated.Identification, purification, and characterization of transpeptidase and glycosyltransferase domains of Streptococcus pneumoniae penicillin-binding protein 1a.Biochemical characterization of Streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance.Transfer of penicillin resistance from Streptococcus oralis to Streptococcus pneumoniae identifies murE as resistance determinant.Interactions between late-acting proteins required for peptidoglycan synthesis during sporulation.On the substrate specificity of bacterial DD-peptidases: evidence from two series of peptidoglycan-mimetic peptidesEffects of low PBP2b levels on cell morphology and peptidoglycan composition in Streptococcus pneumoniae R6.Fluorescent Bocillins: synthesis and application in the detection of penicillin-binding proteins.Kinetics of beta-lactam interactions with penicillin-susceptible and -resistant penicillin-binding protein 2x proteins from Streptococcus pneumoniae. Involvement of acylation and deacylation in beta-lactam resistance.Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae.Characterization of Lactococcus lactis response to ampicillin and ciprofloxacin using surface-enhanced Raman spectroscopy.Increase of the deacylation rate of PBP2x from Streptococcus pneumoniae by single point mutations mimicking the class A beta-lactamases.The membrane anchor of penicillin-binding protein PBP2a from Streptococcus pneumoniae influences peptidoglycan chain length.Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.
P2860
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P2860
Biochemical characterization of penicillin-resistant and -sensitive penicillin-binding protein 2x transpeptidase activities of Streptococcus pneumoniae and mechanistic implications in bacterial resistance to beta-lactam antibiotics.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@en
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@nl
type
label
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@en
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@nl
prefLabel
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@en
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@nl
P2093
P2860
P1476
Biochemical characterization o ...... ce to beta-lactam antibiotics.
@en
P2093
Alborn WE Jr
Carnahan RH
Flokowitsch J
Jaskunas SR
P2860
P304
P356
10.1128/JB.179.15.4901-4908.1997
P577
1997-08-01T00:00:00Z