The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.
about
Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active ZoneCa2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetesTargeting of voltage-gated calcium channel α2δ-1 subunit to lipid rafts is independent from a GPI-anchoring motif.Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release.An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.Cav1.2 and Cav1.3 are differentially coupled to glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells.
P2860
Q26770446-F4377491-0DC3-44DC-8C90-A5634E523760Q30854105-461E1E09-5A87-411B-9F35-E5D6AA329A4BQ33939598-054FF0C9-8ABD-4092-8708-E11C055A10D8Q34963060-87ACC3D0-0AC1-45BC-BE4B-0BF58D784F62Q35006095-B7B1C20A-2BB6-4A11-91EB-BE10A1398F98Q36385160-8A0EC872-4862-4B71-B1BB-328CB3124419Q37416435-79188708-8368-4A9E-853B-C1B26E5D45B8Q37904176-4C1A7A82-E10D-42B8-B8B6-5AD3AC2A1D6EQ38902592-3E74D941-EF8F-4E15-8C4C-0DDB1BD8E94A
P2860
The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The intracellular II-III loops ...... displacement from lipid rafts.
@en
The intracellular II-III loops ...... displacement from lipid rafts.
@nl
type
label
The intracellular II-III loops ...... displacement from lipid rafts.
@en
The intracellular II-III loops ...... displacement from lipid rafts.
@nl
prefLabel
The intracellular II-III loops ...... displacement from lipid rafts.
@en
The intracellular II-III loops ...... displacement from lipid rafts.
@nl
P2093
P2860
P356
P1476
The intracellular II-III loops ...... displacement from lipid rafts.
@en
P2093
Gregory H Hockerman
Guohong Liu
Julie A Przybyla
Marcy L Guerra
Rachel E Jarrard
Sarah Melissa P Jacobo
Val J Watts
P2860
P304
P356
10.1124/JPET.109.150672
P407
P577
2009-04-07T00:00:00Z