Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.
about
Mechanisms of action of glucagon-like peptide 1 in the pancreasCyclic AMP dynamics in the pancreatic β-cellGlucagon-like peptide-1: regulation of insulin secretion and therapeutic potential.Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel.Anchored phosphatases modulate glucose homeostasisAdenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cellsWolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretionThe entero-insular axis: implications for human metabolism.Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism.Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit.Glucagon-like peptide-1 increases myocardial glucose uptake via p38alpha MAP kinase-mediated, nitric oxide-dependent mechanisms in conscious dogs with dilated cardiomyopathyAn improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase ANeomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas.Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal.Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets.Glucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells.Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.Targeting beta-cell cyclic 3'5' adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review.Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisEvolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins.Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJGlucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells.Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cellsMechanisms of insulin secretion in malnutrition: modulation by amino acids in rodent models.New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout miceMultilevel control of glucose homeostasis by adenylyl cyclase 8.A role of PLC/PKC-dependent pathway in GLP-1-stimulated insulin secretion.Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells.A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.cAMP signalling in insulin and glucagon secretion.The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8Free fatty acids increase PGC-1alpha expression in isolated rat islets.Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach
P2860
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P2860
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@ast
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@en
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@nl
type
label
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@ast
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@en
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@nl
altLabel
Type VIII adenylyl cyclase in ...... enerator for glucose and GLP-1
@en
prefLabel
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@ast
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@en
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@nl
P2093
P3181
P1433
P1476
Type VIII adenylyl cyclase in ...... nerator for glucose and GLP-1.
@en
P2093
P2888
P304
P3181
P356
10.1007/S00125-003-1203-8
P407
P577
2003-10-01T00:00:00Z
P5875
P6179
1005326937