p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. - Wikidata - awgldk - TriplyDB

p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.

p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.

http://www.wikidata.org/entity/Q39864596

about

Guidelines for the use and interpretation of assays for monitoring autophagy Pathophysiological mechanisms of death resistance in colorectal carcinoma Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.Regulation of the intracellular localization of Foxo3a by stress-activated protein kinase signaling pathways in skeletal muscle cells ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets Modification of collagen by 3-deoxyglucosone alters wound healing through differential regulation of p38 MAP kinase.SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.Forkhead box protein O3 transcription factor negatively regulates autophagy in human cancer cells by inhibiting forkhead box protein O1 expression and cytosolic accumulation.The role of TLR8 signaling in acute myeloid leukemia differentiation.Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells.Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.Special Agents Hunting Down Women Silent Killer: The Emerging Role of the p38α Kinase.Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a.Survival by self-destruction: a role for autophagy in the placenta?Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway.Sorafenib inhibits p38α activity in colorectal cancer cells and synergizes with the DFG-in inhibitor SB202190 to increase apoptotic response FOXO1 Mediates Vitamin D Deficiency-Induced Insulin Resistance in Skeletal Muscle.Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells.PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.Interferon-β gene-modified human bone marrow mesenchymal stem cells attenuate hepatocellular carcinoma through inhibiting AKT/FOXO3a pathway.Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure.Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophy.GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer.Applications of post-translational modifications of FoxO family proteins in biological functions.Modulating autophagy: a strategy for cancer therapy Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.Posttranslational modification and quality control.Forkhead box class O transcription factors in liver function and disease Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer.Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.Ataxia-telangiectasia mutated (ATM) participates in the regulation of ionizing radiation-induced cell death via MAPK14 in lung cancer H1299 cells.

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P2860

p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.

http://www.wikidata.org/entity/Q39864596

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

p38alpha blockade inhibits col ...... FoxO-dependent transcription.

@en

p38alpha blockade inhibits col ...... FoxO-dependent transcription.

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type

label

p38alpha blockade inhibits col ...... FoxO-dependent transcription.

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p38alpha blockade inhibits col ...... FoxO-dependent transcription.

@nl

prefLabel

p38alpha blockade inhibits col ...... FoxO-dependent transcription.

@en

p38alpha blockade inhibits col ...... FoxO-dependent transcription.

@nl

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P2860

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

The genomic landscapes of human breast and colorectal cancers

Lessons from hereditary colorectal cancer

p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

Death receptor-3, a new E-Selectin counter-receptor that confers migration and survival advantages to colon carcinoma cells by triggering p38 and ERK MAPK activation

Why do cancers have high aerobic glycolysis?

Stressing the role of FoxO proteins in lifespan and disease

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

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colorectal cancer