SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1. - Wikidata - awgldk - TriplyDB

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

http://www.wikidata.org/entity/Q39873008

about

Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1 The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration Epithelial junctions and Rho family GTPases: the zonular signalosome.The interdependence of the Rho GTPases and apicobasal cell polarity.The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly.Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells.Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domains C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.DNA damage induces the accumulation of Tiam1 by blocking β-TrCP-dependent degradation.SUMOylation of the GTPase Rac1 is required for optimal cell migration.Tiam1-regulated osteopontin in senescent fibroblasts contributes to the migration and invasion of associated epithelial cells.ROCK1 feedback regulation of the upstream small GTPase RhoA Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis.The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease.EphA2 signaling following endocytosis: role of Tiam1.The diverse roles of Rac signaling in tumorigenesis Regulation of small GTPases at epithelial cell-cell junctions.NADPH oxidases as therapeutic targets in ischemic stroke.Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer.Src signaling pathways in prostate cancer.ROS-activated calcium signaling mechanisms regulating endothelial barrier function.TIAM1 variants improve clinical outcome in neuroblastoma.Ras and Rho GTPases on the move: The RasGRF connection.Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis.β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity.Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells.Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.VE-cadherin signaling induces EB3 phosphorylation to suppress microtubule growth and assemble adherens junctions.Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner.GEFs: Dual regulation of Rac1 signaling.HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling.The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

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P2860

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

http://www.wikidata.org/entity/Q39873008

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@en

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@nl

type

label

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@en

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@nl

prefLabel

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@en

SRC-induced disassembly of adh ...... on of the rac activator tiam1.

@nl

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J.MOLCEL.2009.02.012

P1433

P1476

SRC-induced disassembly of adh ...... ion of the rac activator tiam1

@en

P2093

Claire Rooney

http://www.w3.org/2001/XMLSchema#string

Michalis Liontos

http://www.w3.org/2001/XMLSchema#string

Simon A Woodcock

http://www.w3.org/2001/XMLSchema#string

Vassilis G Gorgoulis

http://www.w3.org/2001/XMLSchema#string

Vassilis Zoumpourlis

http://www.w3.org/2001/XMLSchema#string

Yvonne Connolly

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639-653

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scholarly article

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10.1016/J.MOLCEL.2009.02.012

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5

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33

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Anthony D Whetton

Angeliki Malliri

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2009-03-01T00:00:00Z

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24200542

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19285946

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phosphorylation