about
P185
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's diseaseMetals and amyloid-beta in Alzheimer's diseaseZinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluidIron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's diseaseCaenorhabditis elegans maintains highly compartmentalized cellular distribution of metals and steep concentration gradients of manganeseEnduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by TauMetal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's diseaseDisturbed copper bioavailability in Alzheimer's diseaseGlutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patientsOxidative stress in psychiatric disorders: evidence base and therapeutic implicationsN-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trialQualitative methods in early-phase drug trials: broadening the scope of data and methods from an RCT of N-acetylcysteine in schizophreniaPresenilin promotes dietary copper uptakeCopper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout miceSynaptically released zinc: physiological functions and pathological effects.Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification.Copper promotes the trafficking of the amyloid precursor proteinAmong vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts.Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease.The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region.A review of β-amyloid neuroimaging in Alzheimer's disease.Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.Mechanisms of copper ion mediated Huntington's disease progressionMitochondrial oxidative stress causes hyperphosphorylation of tau.Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme.SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Altered levels of blood proteins in Alzheimer's disease longitudinal study: Results from Australian Imaging Biomarkers Lifestyle Study of Ageing cohort.Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells.Tat-haFGF14-154 Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1α/XBP1 Pathway.Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain.Syntaxin 5 is required for copper homeostasis in Drosophila and mammalsCopper: from neurotransmission to neuroproteostasisDirect in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans.The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's diseaseMetals and neuroscience.Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease.N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial.
P50
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P50
description
neuroscientist
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neurowetenschapper
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name
Ashley I Bush
@es
Ashley I Bush
@nl
Ashley I. Bush
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Ashley I. Bush
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type
label
Ashley I Bush
@es
Ashley I Bush
@nl
Ashley I. Bush
@en
Ashley I. Bush
@sq
altLabel
Ashley Bush
@en
prefLabel
Ashley I Bush
@es
Ashley I Bush
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Ashley I. Bush
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Ashley I. Bush
@sq
P244
P1053
A-1186-2007
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7201882835
P184
P21
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6150807264218861668
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n2017188049
P31
P3762
P3829
P496
0000-0001-8259-9069
P734
P7859
lccn-n2017188049