Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation. - Wikidata - awgldk - TriplyDB

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.

http://www.wikidata.org/entity/Q31154202

about

Metals and amyloid-beta in Alzheimer's disease Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide Oxidation enhances human serum albumin thermal stability and changes the routes of amyloid fibril formation Numerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic Synapses Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease.Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.Systemic catabolism of Alzheimer's Abeta40 and Abeta42.CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry.The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's Disease Endogenous zinc in neurological diseases.Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.A copper(I) protein possibly involved in the assembly of CuA center of bacterial cytochrome c oxidase.Despite its role in assembly, methionine 35 is not necessary for amyloid beta-protein toxicity Mysterious oligomerization of the amyloidogenic proteins Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides.Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples.Molecular-level examination of Cu2+ binding structure for amyloid fibrils of 40-residue Alzheimer's β by solid-state NMR spectroscopy.Alzheimer's disease & metals: therapeutic opportunities.Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro Methionine sulfoxide reductases preferentially reduce unfolded oxidized proteins and protect cells from oxidative protein unfolding.The neurobiology of zinc in health and disease.Metal homeostasis in Alzheimer's disease.Promotion of oxidative lipid membrane damage by amyloid beta proteins Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons.Links between copper and cholesterol in Alzheimer's disease.Novel therapeutic strategies for the treatment of protein-misfolding diseases.The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype Pharmacotherapeutic targets in Alzheimer's disease Membrane-targeted strategies for modulating APP and Abeta-mediated toxicity.Early onset Alzheimer's disease and oxidative stress.Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle.Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.Modulating metals as a therapeutic strategy for Alzheimer's disease.Truncated and modified amyloid-beta species.

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Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.

http://www.wikidata.org/entity/Q31154202

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2003 nî lūn-bûn

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2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Neurotoxic, redox-competent Al ...... brane by methionine oxidation.

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Neurotoxic, redox-competent Al ...... brane by methionine oxidation.

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Neurotoxic, redox-competent Al ...... brane by methionine oxidation.

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Journal of Biological Chemistry

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Neurotoxic, redox-competent Al ...... brane by methionine oxidation.

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Anna K Tickler

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Colin J Barrow

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Danielle G Smith

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Darryl Carrington

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Deborah Tew

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Feda E Ali

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Giuseppe D Ciccotosto

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Gulcan Kocak

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Kevin J Barnham

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Robert A Cherny

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42959-42965

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scholarly article

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10.1074/JBC.M305494200

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44

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278

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Colin L. Masters

Frances Šeparović

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Irene Volitakis

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2003-08-18T00:00:00Z

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10607409

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12925530

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Alzheimer's disease