Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence.
about
Evolution of lanthipeptide synthetasesLessons learned from the transformation of natural product discovery to a genome-driven endeavorChemical generation and modification of peptides containing multiple dehydroalaninesGenome mining for ribosomally synthesized natural productsLantibiotics from Geobacillus thermodenitrificans.The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisCPseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides.Structural Characterization and Bioactivity Analysis of the Two-Component Lantibiotic Flv System from a Ruminant Bacterium.Bioengineering of a Nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants Nisin F, Q and Z.Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis.Restoration of bioactive lantibiotic suicin from a remnant lan locus of pathogenic Streptococcus suis serotype 2.Saturation mutagenesis of selected residues of the α-peptide of the lantibiotic lacticin 3147 yields a derivative with enhanced antimicrobial activityInsights into the Biosynthesis of Duramycin.The dawning of a 'Golden era' in lantibiotic bioengineering.The challenge of the lantibiotics: synthetic approaches to thioether-bridged peptides.New type non-lantibiotic bacteriocins: circular and leaderless bacteriocins.Discovery and development of lantibiotics; antimicrobial agents that have significant potential for medical application.Increasing the success rate of lantibiotic drug discovery by Synthetic Biology.'Bac' to the future: bioengineering lantibiotics for designer purposes.Advances in the arsenal of tools available enabling the discovery of novel lantibiotics with therapeutic potential.Potentiating the Activity of Nisin against Escherichia coli.Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing.Employing the promiscuity of lantibiotic biosynthetic machineries to produce novel antimicrobials.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Lantibiotic Reductase LtnJ Substrate Selectivity Assessed with a Collection of Nisin Derivatives as Substrates.Identification of essential amino acid residues in the nisin dehydratase NisB.A new quorum-sensing system (TprA/PhrA) for Streptococcus pneumoniae D39 that regulates a lantibiotic biosynthesis gene cluster.Improving the attrition rate of Lanthipeptide discovery for commercial applications.Discovery of a novel lantibiotic nisin O from Blautia obeum A2-162, isolated from the human gastrointestinal tract.Specificity and Application of the Lantibiotic Protease NisP.Processing and Structure of the Lantibiotic Peptide Nso From the Human Gut Bacterium Blautia obeum A2-162 analysed by Mass Spectrometry.
P2860
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P2860
Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Production of a class II two-c ...... machinery and leader sequence.
@en
Production of a class II two-c ...... machinery and leader sequence.
@nl
type
label
Production of a class II two-c ...... machinery and leader sequence.
@en
Production of a class II two-c ...... machinery and leader sequence.
@nl
prefLabel
Production of a class II two-c ...... machinery and leader sequence.
@en
Production of a class II two-c ...... machinery and leader sequence.
@nl
P2093
P2860
P356
P1476
Production of a class II two-c ...... machinery and leader sequence.
@en
P2093
Anneke Kuipers
Gert N Moll
Jacek Lubelski
Jetta J E Bijlsma
Joanna A Majchrzykiewicz
Oscar P Kuipers
P2860
P304
P356
10.1128/AAC.00883-09
P407
P577
2010-01-25T00:00:00Z