Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways.
about
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation responseThe small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alphaDecreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cellsAmino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathwayExpression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cellsA mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitationHalofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.Gene expression and integrated stress response in HepG2/C3A cells cultured in amino acid deficient medium.Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata).Comparative Study on the Cellular and Systemic Nutrient Sensing and Intermediary Metabolism after Partial Replacement of Fishmeal by Meat and Bone Meal in the Diet of Turbot (Scophthalmus maximus L.).The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat dietATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.ATF4-dependent transcription mediates signaling of amino acid limitation.Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.The transcription factor network associated with the amino acid response in mammalian cells.Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction.Remodeling of lipid metabolism by dietary restriction of essential amino acidsThe eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression.Remodeling the integration of lipid metabolism between liver and adipose tissue by dietary methionine restriction in ratsElevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation.EIF2AK4 mutation in pulmonary veno-occlusive disease: A case report and review of the literatureCellular and animal indispensable amino acid limitation responses and health promotion. Can the two be linked? A critical review.Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation.Regulation of the proteome by amino acids.The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation.Short Chemical Ischemia Triggers Phosphorylation of eIF2α and Death of SH-SY5Y Cells but not Proteasome Stress and Heat Shock Protein Response in both SH-SY5Y and T98G Cells.Methionine restriction on lipid metabolism and its possible mechanisms.Cellular responses to individual amino-acid depletion in antibody-expressing and parental CHO cell lines.Fine-tuning PERK signaling for neuroprotection.Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsAdaptive response to l-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts.Looking at the metabolic consequences of the colchicine-based in vivo autophagic flux assayThe impact of dietary methionine restriction on biomarkers of metabolic health.Growing rats respond to a sulfur amino acid-deficient diet by phosphorylation of the alpha subunit of eukaryotic initiation factor 2 heterotrimeric complex and induction of adaptive components of the integrated stress response.A novel autoregulatory loop between the Gcn2-Atf4 pathway and (L)-Proline [corrected] metabolism controls stem cell identity.D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.
P2860
Q24648465-46574EDC-98D5-4533-B713-9FF738721E07Q28834524-C41ABA9E-B4ED-4BE5-A8FB-DBAC71C2FA38Q33689081-EF8138E6-114D-43C3-BCD4-1B204BBE5F86Q33784832-AED2055B-16F8-44DC-9326-F8418AC3FC9AQ33847650-E92B3039-CC15-4819-A499-74BFCB42EACBQ34107392-8DEB7BE5-26EF-404C-95AA-ED0079964532Q34253805-749C794A-0A8D-4FC8-B20B-C857EF80F6CEQ35044566-3755255F-E5F8-4DC2-BB99-23B90CB7250DQ35057755-71E85DE0-8B5E-464B-B5F1-C2F7B81DEE57Q35903804-5BEC456B-7857-4E80-A817-B362C6C05ACEQ36179381-D25BA36E-8649-44AD-9D57-1E35CB6A376EQ36290259-CC3D8B69-0578-4F67-8EB8-EA818A94E13FQ36332920-A538A0A3-CAF2-420D-A7FE-91E903E32FE8Q36655003-7BDDECBA-702B-4F35-9D16-FBDBE695DD34Q36716443-89D1A8A7-E231-4172-A4EB-9EC268C01FFCQ36830376-D2ABD575-BC53-4B8C-A0A0-42330251816FQ36930792-1DA45D0C-BFD7-457D-8102-EB2EB0E2698CQ37031045-43DFA6E5-6312-4A27-9C47-2D744F975C75Q37148513-951ECD6B-4964-40EC-97FF-081B92C2D830Q37193273-817BDD07-D369-44CB-817B-341D4A0EA90BQ37372007-3B23190A-EB20-459C-99B8-3835E7EE5116Q37432106-008EE863-43F0-465D-B791-D971389D8A92Q37522950-F9DF19AE-C327-43D7-9EFB-145768BA7C87Q37605963-D9888CA5-F897-454E-AE15-18501D9391C2Q38056752-F364A863-F346-4E2A-AAD5-E72845542731Q38288682-12021B5A-2624-447D-9586-D1D716967737Q38294157-C2492F2C-745D-4F13-990F-84C0DB712166Q38703345-DDE741C0-4119-4964-A2FD-8A87ACFE774FQ38717414-39CAD070-6FA8-4002-9411-9E7A3C7D7CD8Q38818265-9BA80A53-69D1-45B8-9C4C-9B989B3C4C60Q38828419-34A027F9-0B19-4C68-9C3A-2C997B2B1E5EQ39061197-BCC0AC06-CEB3-474E-ACCF-CCBCB36E3A07Q39393398-09C812EB-CA13-47A4-8ADC-E66B9B8E7096Q39788329-3BF76DF2-642C-4E78-8D99-B9FC1FD1929BQ39881905-611968BD-4998-4505-8A54-4CB3C4558B10Q39978279-B238A7F8-C38A-411C-8761-AA1C23213ECEQ40434831-3A102A8F-07CC-463A-BFF0-DB39ABF68E69Q40538991-F5893461-A862-4C85-860C-C70F9ED4D34DQ41097192-88EE50F5-33AF-4412-A27E-C1A6D60E94C5Q41331053-C7E6E4D6-3FC3-4B09-B9A1-18464AF8C1BC
P2860
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Amino acid limitation regulate ...... and GCN2-independent pathways.
@en
Amino acid limitation regulate ...... and GCN2-independent pathways.
@nl
type
label
Amino acid limitation regulate ...... and GCN2-independent pathways.
@en
Amino acid limitation regulate ...... and GCN2-independent pathways.
@nl
prefLabel
Amino acid limitation regulate ...... and GCN2-independent pathways.
@en
Amino acid limitation regulate ...... and GCN2-independent pathways.
@nl
P2093
P2860
P1433
P1476
Amino acid limitation regulate ...... and GCN2-independent pathways.
@en
P2093
Alain Bruhat
Anne-Catherine Maurin
Christiane Deval
Cédric Chaveroux
Céline Jousse
Dragan Milenkovic
Laurent Parry
Marc Ferrara
Pierre Fafournoux
Valérie Carraro
P2860
P304
P356
10.1111/J.1742-4658.2008.06818.X
P407
P577
2008-12-19T00:00:00Z