EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases. - Wikidata - awgldk - TriplyDB

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

http://www.wikidata.org/entity/Q39906143

about

Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles Potential approaches to the treatment of Ewing's sarcoma Transcriptional control of mitosis: deregulation and cancer RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma.High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors A new aurora in anaplastic thyroid cancer therapy.Ewing sarcoma EWS protein regulates midzone formation by recruiting Aurora B kinase to the midzone Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis New therapeutic targets in soft tissue sarcoma.Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.Targeted therapies for advanced Ewing sarcoma family of tumors.Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells.Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.Molecular profiling of childhood cancer: Biomarkers and novel therapies Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma.Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.EBNA3C regulates p53 through induction of Aurora kinase B.Downstream EWS/FLI1 - upstream Ewing's sarcoma Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease.EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspases Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties.

P2860

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P2860

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

http://www.wikidata.org/entity/Q39906143

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@en

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@nl

type

label

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@en

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@nl

prefLabel

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@en

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

@nl

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P356

1541-7786.MCR-08-0054

P1433

Molecular Cancer Research

P1476

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases

@en

P2093

Akihito Nagano

http://www.w3.org/2001/XMLSchema#string

Aya Matsuhashi

http://www.w3.org/2001/XMLSchema#string

Gou Kawai

http://www.w3.org/2001/XMLSchema#string

Iori Takigami

http://www.w3.org/2001/XMLSchema#string

Katsuji Shimizu

http://www.w3.org/2001/XMLSchema#string

Kazuhiko Wakahara

http://www.w3.org/2001/XMLSchema#string

Masashi Kimura

http://www.w3.org/2001/XMLSchema#string

Mitsuru Saitoh

http://www.w3.org/2001/XMLSchema#string

Taikoh Dohjima

http://www.w3.org/2001/XMLSchema#string

Takahiro Masuda

http://www.w3.org/2001/XMLSchema#string

P304

1937-1945

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/1541-7786.MCR-08-0054

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P433

12

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P478

6

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P50

P577

2008-12-01T00:00:00Z

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P698

19074838

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