Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance
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MicroRNA and signal transduction pathways in tumor radiation responseNF-κB potentiates caspase independent hydrogen peroxide induced cell deathA novel miRNA-based predictive model for biochemical failure following post-prostatectomy salvage radiation therapyPARP inhibitor treatment in ovarian and breast cancerThe combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line.Changes in hippocampal gene expression by 7-nitroindazole in rats submitted to forced swimming stress.Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers.HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair.NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression.Beyond DNA Repair: Additional Functions of PARP-1 in Cancer.Carbon ions of different linear energy transfer (LET) values induce apoptosis & G2 cell cycle arrest in radio-resistant melanoma cells.Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.HIF-α/MIF and NF-κB/IL-6 axes contribute to the recruitment of CD11b+Gr-1+ myeloid cells in hypoxic microenvironment of HNSCC.Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy.The diverse and complex roles of NF-κB subunits in cancer.DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out.Predictive biomarkers for cancer therapy with PARP inhibitors.Transcriptional roles of PARP1 in cancer.NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699.Long noncoding RNA HAS2-AS1 mediates hypoxia-induced invasiveness of oral squamous cell carcinoma.Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation.Role of interleukin-6 in cancer progression and therapeutic resistance.Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy.Proteasome inhibitor MG132 enhances the antigrowth and antimetastasis effects of radiation in human nonsmall cell lung cancer cells.Radiation-induced inflammatory cascade and its reverberating crosstalks as potential cause of post-radiotherapy second malignancies.Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines.Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.Simvastatin ameliorates ionizing radiation-induced apoptosis in the thymus by activating the AKT/sirtuin 1 pathway in mice.Anti-apoptotic effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, against multiple organ damage induced by gamma irradiation in rats.Poly(ADP-ribose) polymerase activation mediates synchrotron radiation X-ray-induced damage of rodent testes by exacerbating DNA damage and apoptotic changes.The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma.Ginsenoside Rg3 Sensitizes Colorectal Cancer to Radiotherapy through Downregulation of Proliferative and Angiogenic Biomarkers.mGluR5 mediates post-radiotherapy fatigue development in cancer patients.Oct4 suppresses IR‑induced premature senescence in breast cancer cells through STAT3- and NF‑κB-mediated IL‑24 production.
P2860
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P2860
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
@zh-hant
name
Ionizing radiation-induced NF- ...... tion to confer radioresistance
@en
Ionizing radiation-induced NF- ...... ion to confer radioresistance.
@nl
type
label
Ionizing radiation-induced NF- ...... tion to confer radioresistance
@en
Ionizing radiation-induced NF- ...... ion to confer radioresistance.
@nl
prefLabel
Ionizing radiation-induced NF- ...... tion to confer radioresistance
@en
Ionizing radiation-induced NF- ...... ion to confer radioresistance.
@nl
P2093
P2860
P356
P1433
P1476
Ionizing radiation-induced NF- ...... tion to confer radioresistance
@en
P2093
B W Durkacz
J E Hunter
S J Veuger
P2860
P2888
P304
P356
10.1038/ONC.2008.439
P407
P577
2008-12-08T00:00:00Z