Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
about
Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1BCalpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of diseaseCalpain-1 deletion impairs mGluR-dependent LTD and fear memory extinctionMolecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpainAssociation of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells.beta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2ACalpain protects the heart from hemodynamic stress.PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.Calpain modulates cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in cells of the osteoblast lineage.Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity.Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma.Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network.Overview of calpain-mediated regulation of bone and fat mass in osteoblasts.Calpain restrains the stem cells compartment in breast cancer.Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosisMiR-99a and MiR-491 Regulate Cisplatin Resistance in Human Gastric Cancer Cells by Targeting CAPNS1.The calpain system and cancer.Pericyte-expressed Tie2 controls angiogenesis and vessel maturation.Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptorsFasL gene knock-down therapy enhances the antiglioma immune response.Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.Calpain-activated mTORC2/Akt pathway mediates airway smooth muscle remodelling in asthma.Calpain7 impairs embryo implantation by downregulating β3-integrin expression via degradation of HOXA10.Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition.Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
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P2860
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@en
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@nl
type
label
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@en
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@nl
prefLabel
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@en
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@nl
P2093
P2860
P356
P1433
P1476
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2008.425
P407
P577
2008-11-24T00:00:00Z
P5875
P6179
1026710158