Implication of the JNK pathway in a rat model of Huntington's disease.
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Therapeutic targets in the ASK1-dependent stress signaling pathwaysA novel multiplex cell viability assay for high-throughput RNAi screeningInhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's diseaseSynchrotron infrared microspectroscopy detecting the evolution of Huntington's disease neuropathology and suggesting unique correlates of dysfunction in white versus gray brain matter.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.A common gene expression signature in Huntington's disease patient brain regions.Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.Comparison of modules of wild type and mutant Huntingtin and TP53 protein interaction networks: implications in biological processes and functions.Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in DrosophilaMAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibitionHTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of diseasec-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axisAttenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains.JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay.Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease.Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract.Beneficial effect of (-)schisandrin B against 3-nitropropionic acid-induced cell death in PC12 cells.
P2860
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P2860
Implication of the JNK pathway in a rat model of Huntington's disease.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Implication of the JNK pathway in a rat model of Huntington's disease.
@en
Implication of the JNK pathway in a rat model of Huntington's disease.
@nl
type
label
Implication of the JNK pathway in a rat model of Huntington's disease.
@en
Implication of the JNK pathway in a rat model of Huntington's disease.
@nl
prefLabel
Implication of the JNK pathway in a rat model of Huntington's disease.
@en
Implication of the JNK pathway in a rat model of Huntington's disease.
@nl
P2093
P1476
Implication of the JNK pathway in a rat model of Huntington's disease.
@en
P2093
P304
P356
10.1016/J.EXPNEUROL.2008.10.008
P407
P577
2008-10-28T00:00:00Z