Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes. - Wikidata - awgldk - TriplyDB

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes.

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes.

http://www.wikidata.org/entity/Q39918550

about

Chromosome identification and its application in Chinese hamster ovary cells FISH-Based Analysis of Clonally Derived CHO Cell Populations Reveals High Probability for Transgene Integration in a Terminal Region of Chromosome 1 (1q13).Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification.Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production.Identification of regulatory motifs in the CHO genome for stable monoclonal antibody production.Recombinase-mediated cassette exchange (RMCE) for monoclonal antibody expression in the commercially relevant CHOK1SV cell line.Assessment of UCOE on Recombinant EPO Production and Expression Stability in Amplified Chinese Hamster Ovary Cells.Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering.Construction of BAC-based physical map and analysis of chromosome rearrangement in Chinese hamster ovary cell lines.A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.Screening for improved cell performance: selection of subclones with altered production kinetics or improved stability by cell sorting.Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH.Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.Construction of a gene knockout CHO cell line using a simple gene targeting method.Stability difference of each chromosome in Chinese Hamster Ovary cell line.Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.A single-plasmid vector for transgene amplification using short hairpin RNA targeting the 3'-UTR of amplifiable dhfr.

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P2860

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes.

http://www.wikidata.org/entity/Q39918550

description

2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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2000年學術文章

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2000年學術文章

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name

Evaluation of stable and highl ...... e location of amplified genes.

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Evaluation of stable and highl ...... e location of amplified genes.

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type

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Evaluation of stable and highl ...... e location of amplified genes.

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Evaluation of stable and highl ...... e location of amplified genes.

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Evaluation of stable and highl ...... e location of amplified genes.

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Evaluation of stable and highl ...... e location of amplified genes.

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Evaluation of stable and highl ...... e location of amplified genes.

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P2860

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization

Complete nucleotide sequence of SV40 DNA.

Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary dna gene.

Identification of methotrexate transport deficiency in mammalian cells using fluoresceinated methotrexate and flow cytometry

Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events.

New mechanisms of gene amplification in drug resistance (the episome model).

Chromosomal destabilization during gene amplification.

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