FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. - Wikidata - awgldk - TriplyDB

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts.

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts.

http://www.wikidata.org/entity/Q39922407

about

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles Interplay between Fanconi anemia and homologous recombination pathways in genome integrity G-quadruplexes and helicases G-quadruplexes and their regulatory roles in biology Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome Replication fork instability and the consequences of fork collisions from rereplication G-quadruplexes in pathogens: a common route to virulence control?Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis The G4 genome BLM helicase facilitates telomere replication during leading strand synthesis of telomeres Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutations Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.Molecular analyses of DNA helicases involved in the replicational stress response.G-quadruplex nucleic acids and human disease Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination.Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.Telomeres: structures in need of unwinding.Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer.Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia DNA and RNA quadruplex-binding proteins.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.Helicase-inactivating mutations as a basis for dominant negative phenotypes.Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells.Lead Exposure Induces Telomere Instability in Human Cells Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1.A distinct triplex DNA unwinding activity of ChlR1 helicase

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FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts.

http://www.wikidata.org/entity/Q39922407

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-my

2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@en

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@nl

type

label

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@en

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@nl

prefLabel

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@en

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@nl

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P1433

Journal of Biological Chemistry

P1476

FANCJ is a structure-specific ...... tenance of genomic G/C tracts.

@en

P2093

Georgina Mosedale

http://www.w3.org/2001/XMLSchema#string

Ian D Hickson

http://www.w3.org/2001/XMLSchema#string

Kevin Hiom

http://www.w3.org/2001/XMLSchema#string

Shankar Balasubramanian

http://www.w3.org/2001/XMLSchema#string

Simon J Boulton

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Timothy B C London

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P2860

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer

Prevalence of quadruplexes in the human genome.

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations

The emerging genetic and molecular basis of Fanconi anaemia

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein

P304

36132-36139

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scholarly article

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10.1074/JBC.M808152200

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P433

52

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P478

283

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Louise J Barber

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2008-10-31T00:00:00Z

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23445801

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18978354

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2662291

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