E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors - Wikidata - awgldk - TriplyDB

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors

http://www.wikidata.org/entity/Q39926821

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Factors and networks that underpin early hematopoiesis Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.Smurf2 regulates hematopoietic stem cell self-renewal and aging.From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.Hematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in hematopoietic stem cells Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid development E proteins and the regulation of early lymphocyte development Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice.E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction.Chronic exposure to a TLR ligand injures hematopoietic stem cells.The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells.Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway.The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor.Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.Cutting Edge: Hematopoietic Stem Cell Expansion and Common Lymphoid Progenitor Depletion Require Hematopoietic-Derived, Cell-Autonomous TLR4 in a Model of Chronic Endotoxin.Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation.The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages.Regulation of P2X(7) gene transcription.Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.E and ID proteins branch out.E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a Hoxa9 regulates Flt3 in lymphohematopoietic progenitors.P2X7-mediated chemoprevention of epithelial cancers.T-cell lineage determination.Molecular resolution of the B cell landscape.Transcriptional and epigenetic regulation of B cell development.Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells.The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.Cell-intrinsic in vivo requirement for the E47-p21 pathway in long-term hematopoietic stem cells Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.Developmental trajectories in early hematopoiesis.Deciding the decider: Mef2c in hematopoiesis.

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P2860

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors

http://www.wikidata.org/entity/Q39926821

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2008 nî lūn-bûn

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2008年の論文

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name

E47 controls the developmental ...... tial hematopoietic progenitors

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E47 controls the developmental ...... ial hematopoietic progenitors.

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E47 controls the developmental ...... tial hematopoietic progenitors

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E47 controls the developmental ...... ial hematopoietic progenitors.

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E47 controls the developmental ...... tial hematopoietic progenitors

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E47 controls the developmental ...... ial hematopoietic progenitors.

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JIMMUNOL.181.9.5885

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Journal of Immunology

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E47 controls the developmental ...... tial hematopoietic progenitors

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P2093

Anthony St Leger

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Barbara Varnum-Finney

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Christine Milcarek

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Irwin D Bernstein

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Kathleen Martincic

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Lela Kardava

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Lisa Borghesi

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Qi Yang

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P2860

Promotion of cell cycle progression by basic helix-loop-helix E2A

Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction

Gradient of E2A activity in B-cell development.

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

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5885-5894

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scholarly article

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10.4049/JIMMUNOL.181.9.5885

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9

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181

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2008-11-01T00:00:00Z

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23403177

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18941177

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2597624

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