A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors.
about
Ly6 family proteins in neutrophil biologyNew selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction.C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinomaNeutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Characterization and function of human Ly-6/uPAR molecules.Proteinase 3-ANCA Vasculitis versus Myeloperoxidase-ANCA Vasculitis.A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia.How anti-neutrophil cytoplasmic autoantibodies activate neutrophils.Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).Proteinase 3 Is a Phosphatidylserine-binding Protein That Affects the Production and Function of Microvesicles.Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.Optimizing the translational value of animal models of glomerulonephritis: insights from recent murine prototypes.Neutral serine proteases of neutrophils.Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener's autoantigen, in RBL cells: implication for its pathogenic activity.Discrimination and variable impact of ANCA binding to different surface epitopes on proteinase 3, the Wegener's autoantigen.Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils.Characterization of the CD177 interaction with the ANCA antigen proteinase 3.Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.Catalytic activity and inhibition of wegener antigen proteinase 3 on the cell surface of human polymorphonuclear neutrophils.Rapid enzyme-linked immunosorbent assay for the detection of antibodies against human neutrophil antigens -1a, -1b, and -1c.Interaction of serine proteases from polymorphonuclear leucocytes with the cell surface and heparin.Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.Anti-neutrophil cytoplasmic antibodies target sequential functional proteinase 3 epitopes in the sera of patients with Wegener’s granulomatosis.A novel enzyme-linked immunosorbent assay method for the detection of human neutrophil antigen-2a antibodies.The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions.Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis
P2860
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P2860
A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@en
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@nl
type
label
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@en
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@nl
prefLabel
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@en
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@nl
P2093
P2860
P356
P1476
A hydrophobic patch on protein ...... ane binding via NB1 receptors.
@en
P2093
Angelika Kuhl
Behnaz Bayat
Brice Korkmaz
Dieter E Jenne
P2860
P304
35976-35982
P356
10.1074/JBC.M806754200
P407
P577
2008-10-14T00:00:00Z