The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. - Wikidata - awgldk - TriplyDB

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway.

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway.

http://www.wikidata.org/entity/Q39933047

about

Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice.Recent advances in the regulation of cholangiocarcinoma growth Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism.Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology.Recent advances in the understanding of the role of the endocannabinoid system in liver diseases.Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion.Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.Suppression of the HPA Axis During Cholestasis Can Be Attributed to Hypothalamic Bile Acid Signaling.The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.Activated macrophages promote Wnt/β-catenin signaling in cholangiocarcinoma cells.Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management.Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma.Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes.Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice.TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.TGFβ1 exacerbates blood-brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5 Changes in the endocannabinoid system may give insight into new and effective treatments for cancer.Update on the endocannabinoid system as an anticancer target.The roles of transforming growth factor-β, Wnt, Notch and hypoxia on liver progenitor cells in primary liver tumours (Review).Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).Increased local dopamine secretion has growth-promoting effects in cholangiocarcinoma.Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor.The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration.Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling.Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms.Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer.Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents.NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury.Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids.INSIGHT ON THE IMPACT OF ENDOCANNABINOID SYSTEM IN CANCER: A REVIEW.FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy.

P2860

Q28075903-747F8AFF-D532-469A-8A07-1E6E05626763 Q28273377-EE31182C-981D-4FB1-832D-2BCF4827530A Q33870953-C4D5AAD5-F16D-4EAB-9D54-945709B0B125 Q33994814-4C474950-FA4C-4379-AFA9-48E4AF1C10A4 Q34027245-866AB1CC-A2CF-4F26-BFD8-5AE2122898CF Q34064728-276385E0-D534-4853-A182-C24F38E206C5 Q34358007-BB93BB65-B14F-4146-905C-3C59D8F5C2ED Q34550846-E3BE93A2-A8AA-4E28-B6BA-A92F4A5E890F Q34979300-04A356ED-E43F-49A8-957C-2D523EA79900 Q35629462-086A3F1C-5E4B-4DCB-9033-D2A7DF57D02E Q35841978-A8B2EA82-297F-492E-9BA9-CAC7021A1667 Q35939397-18ECFA44-D29E-4D28-9DB1-C4A8E9240E18 Q36331780-BC21BF5C-0C13-4988-B14C-8B73C812AD55 Q36494373-08F872A6-4810-4EBF-8758-03CA607380BD Q36509199-571D0904-67D6-4881-98B5-4929E59D48E8 Q36887069-C73AD3DF-07EB-478B-A8DA-A93E5F19CC4E Q36996563-0A4DFB63-6FC6-4E21-9215-CC9A4A33E006 Q37028411-7AADD005-979B-4515-9610-31FB13B972EB Q37062591-1B498C2C-7655-4C43-90FD-AF159BCB9CBA Q37209413-B6A4FA4F-8162-4D5A-B711-F9841E7D6243 Q37272976-7DF5F27C-8CB2-40E5-99F2-DC936DED2300 Q37292152-C99AE99B-030B-42C8-AB0D-84F9942F51B6 Q37568679-2F5FFBC6-33E4-4B89-AB2D-E0FFF2E16EEF Q37829751-1A8DC902-A577-4F63-8A1E-DC4FD4A419C5 Q38185910-CCAB97CB-42A1-4393-9EA5-E037ABC4BE6F Q38812588-5DC3A69C-489B-48B1-82B9-C2AD667682DA Q39340369-3711ABE7-3CB3-4E03-BB20-A9FD994806D9 Q39564556-5E0FFB91-0099-4141-9D03-410D60A84931 Q39774062-6E061777-C6B7-47EA-A652-5E53967DA092 Q40620117-E7017580-145E-4F72-B585-C3D9F82F54AA Q40958306-005903B3-88B1-4452-977B-E5907C4B0090 Q41718159-E5C3F513-DF64-48ED-B6E4-11CB4B909874 Q41935784-608A89B5-3A97-49A6-926C-261CA70B9FC7 Q45057004-629F9146-EF6A-4580-9A46-EDBF6F4494CE Q47813887-FF85E09F-EC94-4052-A000-FB39E5465306 Q49237718-FDA584BF-7A48-4F13-A283-CB9055838D9F Q52583978-2EC8F5E7-3DA7-4B86-94E2-58B30C3870C3 Q55263156-5C4BB318-5A07-403D-A56D-EBA74A153605

P2860

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway.

http://www.wikidata.org/entity/Q39933047

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@en

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@nl

type

label

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@en

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@nl

prefLabel

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@en

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@nl

P1433

Q39933047-9CD49F8D-9981-47A1-8963-50296E8C22E6

P1476

Q39933047-B2879389-8DEB-41E5-85EC-68415757E68C

P2093

Q39933047-17661E4E-3C68-41EE-A2A3-E99D16A00F5A

Q39933047-1B2BEDC5-D2A2-4116-9C5C-4F4180938F4E

Q39933047-54DEFC88-FFFE-4EC6-B4B3-B0BE1CD82F63

Q39933047-5AEC4AF7-9613-4005-8F33-382137CD9324

Q39933047-5D502777-B6F8-4056-9BDA-5162CF4B02A3

Q39933047-6BE7E630-0486-4B97-BE02-1034BC8D4E57

Q39933047-94026712-968D-4DEE-8C6E-1774926F9F9D

Q39933047-A8B2BA63-459C-471B-98BF-C3425518DB72

Q39933047-C68B4BB4-5207-49FB-B386-0086F97F4106

Q39933047-D9CBE42C-8721-40A2-88CB-830143652880

P2860

Q39933047-00D65002-8735-423E-9DA4-0F71A924A7E4

Q39933047-036718D8-C102-4B3E-8E34-44912917840C

Q39933047-0AEB79C8-EE6D-4251-B7BE-631B1E9B73A0

Q39933047-0C2D6432-291D-493B-B330-27E25ABDF82F

Q39933047-1078D178-8DE2-47D3-A559-3BD165822D0C

Q39933047-23241D0A-7445-4B1A-B0DD-79CFE7224716

Q39933047-2FCA933D-D291-47D1-ACC1-436215224715

Q39933047-34DC99FB-B46D-4CA7-B947-DEA5D4BE3D2A

Q39933047-35FC838E-0A36-494C-821A-1816CE69593F

Q39933047-3A65F4D9-7BBC-4CE7-A777-22F41229AB33

P304

Q39933047-1B4B8E7F-6B6C-412F-BBDF-5F895780F6E9

P31

Q39933047-AABAA0D5-7B42-418A-ADF9-5CCB7D3495B7

P356

Q39933047-87BF1E70-7340-4EB8-8E02-B13E7BD6EEBD

P433

Q39933047-B0F83063-71B9-4996-AFF3-C60B540B43E7

P478

Q39933047-EF686335-CD1B-45EE-9F45-282FF994E67D

P50

Q39933047-AC1F34D9-5AC9-444F-86A7-EB7D79EBA72A

P577

Q39933047-DC91B3C2-B5B1-4933-8195-4FAEF47D9766

P5875

Q39933047-E207FC78-406A-4831-BB98-658B02FDBFC3

P698

Q39933047-D5C15D48-BA54-4B44-81C9-8FF8FB35E7BE

P921

Q39933047-27F05728-3F97-4B3A-B8E1-D8342B44150A

Q39933047-63C10171-F9EC-44CD-B9DF-397C315583E6

Q39933047-BA2E38F6-C519-4E5F-9463-81FD19CC04B9

Q39933047-DCF42EDF-80E9-41D0-A702-DA058F63C4EE

P932

Q39933047-EA48EF12-18EF-4947-88DF-FE2CF6940E5A

P356

AJPGI.90455.2008

P1433

American Journal of Physiology - Gastrointestinal and Liver Physiology

P1476

The endocannabinoid anandamide ...... nonical Wnt signaling pathway.

@en

P2093

Antonio Franchitto

http://www.w3.org/2001/XMLSchema#string

Bradley Vaculin

http://www.w3.org/2001/XMLSchema#string

Brett Mitchell

http://www.w3.org/2001/XMLSchema#string

Eugenio Gaudio

http://www.w3.org/2001/XMLSchema#string

Gabriel Frampton

http://www.w3.org/2001/XMLSchema#string

Gianfranco Alpini

http://www.w3.org/2001/XMLSchema#string

Heather Francis

http://www.w3.org/2001/XMLSchema#string

Julie Venter

http://www.w3.org/2001/XMLSchema#string

Monique Coufal

http://www.w3.org/2001/XMLSchema#string

Romina Mancinelli

http://www.w3.org/2001/XMLSchema#string

P2860

Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration

Cannabinoids control spasticity and tremor in a multiple sclerosis model

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

Wnt-5a has tumor suppressor activity in thyroid carcinoma

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism

Angiogenesis as a therapeutic target

Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration

Pharmacological and biochemical interactions between opioids and cannabinoids.

Wnt signalling in mammalian development and cancer.

P304

G1150-8

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/AJPGI.90455.2008

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

295

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-10-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23297013

http://www.w3.org/2001/XMLSchema#string

P698

18832445

http://www.w3.org/2001/XMLSchema#string

P921

cholangiocarcinoma

endocannabinoids

P932

2604798

http://www.w3.org/2001/XMLSchema#string