Functional interactions within 23S rRNA involving the peptidyltransferase center.
about
Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current SolutionsSynthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cellsProtein folding by domain V of Escherichia coli 23S rRNA: specificity of RNA-protein interactionsUGA suppression by a mutant RNA of the large ribosomal subunit.Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21.Macrolide resistance conferred by base substitutions in 23S rRNA.High-level azithromycin resistance occurs in Neisseria gonorrhoeae as a result of a single point mutation in the 23S rRNA genesRibosomal protein gene sequence changes in erythromycin-resistant mutants of Escherichia coli.Alterations in the peptidyltransferase and decoding domains of ribosomal RNA suppress mutations in the elongation factor G gene.A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit.Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes.Identification of a novel G2073A mutation in 23S rRNA in amphenicol-selected mutants of Campylobacter jejuniResponses of wild-type and resistant strains of the hyperthermophilic bacterium Thermotoga maritima to chloramphenicol challenge.Antibiotic drugs targeting bacterial RNAs.The ribosomal peptidyl transferase center: structure, function, evolution, inhibition.Structural basis for cross-resistance to ribosomal PTC antibiotics.Tools for characterizing bacterial protein synthesis inhibitors.Reactivation of denatured proteins by 23S ribosomal RNA: role of domain V.A conserved secondary structural motif in 23S rRNA defines the site of interaction of amicetin, a universal inhibitor of peptide bond formation.Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin.Resistance to Macrolide Antibiotics in Public Health Pathogens.Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance.Conjugation with polyamines enhances the antibacterial and anticancer activity of chloramphenicol.Two new point mutations at A2062 associated with resistance to 16-membered macrolide antibiotics in mutant strains of Mycoplasma hominis.Mutations in domain V of the 23S ribosomal RNA of Bacillus subtilis that inactivate its protein folding property in vitro.Reactivation of denatured proteins by domain V of bacterial 23S rRNA.Erythromycin resistance by ribosome modification.Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferaseThe antibiotics micrococcin and thiostrepton interact directly with 23S rRNA nucleotides 1067A and 1095A.A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.Cooperative assembly of proteins in the ribosomal GTPase centre demonstrated by their interactions with mutant 23S rRNAs.Interaction of the antibiotics clindamycin and lincomycin with Escherichia coli 23S ribosomal RNA.Structure and function of 5S rRNA in the ribosome.Pleiotropic effects of mutations at positions 13 and 914 in Escherichia coli 16S ribosomal RNA.Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants.Movement of the 3'-end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics.The conformation of 23S rRNA nucleotide A2058 determines its recognition by the ErmE methyltransferase.Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.
P2860
Q26748249-5593D74F-C46E-4E67-B4EB-AEA3AC0F198AQ28547167-27D8D0A1-BFFF-4125-B8AF-3656ACF7C94EQ33321822-13A6EB94-2B1F-4E59-AAD9-885308E34E4EQ33667818-C530968C-DB6E-4130-8C86-9A04691C8EE8Q33787419-189E0066-1EA3-4815-A272-18C162FAA17AQ33996568-60AEF6A9-8FC4-40F9-91C6-AFB2218E103DQ34106180-FEF6DE88-D06B-4405-8B29-001E200202A9Q34108807-CF1B65E3-03B5-48FB-A6B2-4DDF83CD4EFFQ34323549-E7A87CC4-4582-4FC4-BD42-710A12BEA8C1Q34362923-F78D2A59-027F-4134-8C17-0EB7C8678495Q35037268-1455F391-B19C-444F-A960-48B5B658DF2AQ35065843-2CA86765-98C8-48E9-A7AC-9AB5DACBA068Q35139442-EEDF027B-0F4F-4355-AF5C-83D2D0F9828AQ35146655-86E3561A-AB30-4823-86D6-3CEBF0E82B0AQ35946804-414F12A9-B245-4333-BE93-37F9E73DD76BQ36237579-379F2FC3-C30F-4817-8E60-A9B5C2BC0897Q36300790-0F6222AA-EDDE-42F3-91F3-37169D7D2DE9Q37020720-474F9F2D-98CD-4E27-83DD-770E6422486BQ37335642-B63C7AF8-FED2-44F3-B2BD-DB834F65A3D3Q37399401-3C9FE630-0437-4909-B7C0-A72490C63393Q37630762-196061E8-45A9-49A6-B50A-EBFDC5F33EC9Q38804355-5150D0A7-1752-4F5D-A671-F14832DCC456Q38928353-96FF61B2-7D0A-4B62-BF44-FF6A358E33A9Q38934153-167DD710-453C-4151-820D-AAA1F4E57DA0Q38983564-6B7EB127-E7D8-45C9-8AE1-8B04397B459DQ39478683-3639C353-F8BC-457A-8D1C-28F0B5F18335Q39535155-1D9F6D6D-F481-4BFB-8639-F007F46379D9Q39721940-FF10A146-DC72-4E0B-A6C7-9640188FC124Q39779280-A3C5C788-555F-459C-8CCD-750B4A5EF972Q39899065-EB2E4A16-FE91-4873-B5CD-51DD1DF63C4BQ40225357-57CA6C38-7879-4BD2-AB75-6990F9595E55Q40324068-A5335B92-36E0-4817-991B-740CE417E720Q40394690-E7AE11E8-CC20-4528-9E59-6D3923E4507FQ40534214-0246B643-9A9C-4D24-A097-06FF4D173B92Q41043656-507D9F4C-3C58-4B89-8165-A13BCED167D6Q41043681-5AD2F8C2-D9A6-43A9-8A04-F7E642172A7BQ41177995-AE2ED1BB-0402-4AE8-A4E9-A3411418D11BQ41459582-3F420757-8CD3-4327-8A3E-1454104D5441Q41953809-CC8E531B-B6BC-480E-B5C1-F2DA110AC853Q41971295-60476530-4063-4BC7-8AA2-12FCB76C640A
P2860
Functional interactions within 23S rRNA involving the peptidyltransferase center.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@en
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@nl
type
label
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@en
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@nl
prefLabel
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@en
Functional interactions within 23S rRNA involving the peptidyltransferase center.
@nl
P2860
P1476
Functional interactions within 23S rRNA involving the peptidyltransferase center
@en
P2093
Douthwaite S
P2860
P304
P356
10.1128/JB.174.4.1333-1338.1992
P577
1992-02-01T00:00:00Z