Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover
about
Replication-Associated Recombinational Repair: Lessons from Budding YeastDNA damage tolerance by recombination: Molecular pathways and DNA structuresHold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1Nucleases in homologous recombination as targets for cancer therapyMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeDNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Length-dependent processing of telomeres in the absence of telomerase.SUMO-mediated regulation of DNA damage repair and responsesXPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage.Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA associationVisualization of recombination-mediated damage bypass by template switching.DNA structure-specific priming of ATR activation by DNA-PKcsA physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repairError-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 ComplexDampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 PhosphataseThe Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression.Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cellsMph1 and Mus81-Mms4 prevent aberrant processing of mitotic recombination intermediatesResolution by unassisted Top3 points to template switch recombination intermediates during DNA replication.Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1.Nucleolytic processing of aberrant replication intermediates by an Exo1-Dna2-Sae2 axis counteracts fork collapse-driven chromosome instability.Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains.Resolution of single and double Holliday junction recombination intermediates by GEN1.Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosisThe Intra-S Checkpoint Responses to DNA Damage.Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities.Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.Holliday junction resolution: regulation in space and time.DNA damage repair machinery and HIV escape from innate immune sensing.Holliday junction resolvases.Resolution of Recombination Intermediates: Mechanisms and Regulation.Substrate specificity of the MUS81-EME2 structure selective endonuclease.Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability.Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast.
P2860
Q26739929-80AC5CF9-4AF1-4D99-85BE-D662A4D09CC6Q26745490-FFBE0D81-1EC5-455E-80FF-0EA775D08FE0Q26797303-24A3045F-8835-4D79-A9B9-10864B6BEE24Q26822478-D696BEC9-2B81-4049-9D44-9DB91BA3CC9DQ26864428-B819BF9F-CC8F-4AC0-846A-3C17CD2AE23AQ27933423-4E0FE161-8CF2-4A8B-A2F6-F331F2CEB90BQ27934018-705C3A00-5343-40A4-A7A6-AB28F36BA446Q27940191-E3D99BAD-5535-4FA3-ADC6-66CC42727E91Q27940217-8DB6D0B3-323E-4647-884F-244A9507EC0FQ28086764-3ABCD032-1607-461E-B606-237E2532D8F5Q28238027-3CC14DA9-F264-48DF-8A64-8871352AA8D7Q33698561-52433ECC-59D3-4CC0-9F20-242371106861Q33698685-C5EB06F8-0794-41A0-AF06-D97BDE4CC3C4Q34307346-EA624366-CFE5-4F92-A6B1-70116C18975DQ34880194-FA0523C1-A5DF-485D-80AB-97BBFA63804DQ35089067-0F55E50C-D3B5-4853-8AE4-6AB33AD820B2Q35156821-980F0174-A7AD-4C6B-BCAB-422FFFCBA359Q35762655-1BC702A5-993A-4467-A481-15B477F2B0D1Q36158128-DC986762-7D30-4D73-A76A-4862831F64E0Q36291440-254828E7-ECBB-4B95-A510-FC3FA7E280D7Q36744498-FA04B076-B24C-47B2-8A52-3404A72F84D5Q36775519-BA1FF04B-6E56-4F80-8599-E88AFB728D4DQ37271812-2E8EC3F7-86A8-414C-A374-6CF338426131Q37283116-43227D7B-AB35-4850-BBDA-519C787EEE8DQ37311395-2463D465-23AC-49D3-9C58-E11226616207Q37389940-0212F66E-8D0B-4D09-9EE6-DEA459E64290Q37507614-D968FC41-AC2D-45FA-8058-CD93A4ADF6D7Q37577441-7D4C35E0-6589-471E-A6DA-C620B76E026FQ37599023-14E7DA4F-5F9C-4B7B-9BF1-F1E52DB34F90Q37673546-2A90CB03-6945-41F8-9173-B76B59C8360CQ37676255-90713CD7-9330-41E0-A7CD-AFE1686323B1Q37724141-1AC9A857-0D90-4B4E-97A3-FC61604D1A82Q38134624-CC12AEE8-E3D3-4D91-A56C-EF76C4DB68F4Q38207298-3EFF9720-0BD8-4D81-9BA9-D66E3A4C4D6AQ38209320-676667C3-B7BF-415A-92AC-28657EA7FB4DQ38245723-A3AC8227-7DB9-4957-8C5B-BA184C2AD970Q38586814-6302ACFB-53FA-4909-8044-9219D86BC9AFQ38593922-CD0897EB-8BEB-4AD7-87A8-9831993C8509Q38786931-7C9A56F9-B911-45CF-A406-E19CAEAD71E5Q38831197-A5C18A7E-24DD-405E-975A-D442320BA7BA
P2860
Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Premature Cdk1/Cdc5/Mus81 path ...... tion and deleterious crossover
@en
Premature Cdk1/Cdc5/Mus81 path ...... ion and deleterious crossover.
@nl
type
label
Premature Cdk1/Cdc5/Mus81 path ...... tion and deleterious crossover
@en
Premature Cdk1/Cdc5/Mus81 path ...... ion and deleterious crossover.
@nl
prefLabel
Premature Cdk1/Cdc5/Mus81 path ...... tion and deleterious crossover
@en
Premature Cdk1/Cdc5/Mus81 path ...... ion and deleterious crossover.
@nl
P2860
P356
P1433
P1476
Premature Cdk1/Cdc5/Mus81 path ...... tion and deleterious crossover
@en
P2860
P304
P356
10.1038/EMBOJ.2013.67
P407
P577
2013-03-26T00:00:00Z